FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2568593465> ?p ?o ?g. }

• W2568593465 endingPage "e0169466" @default.
• W2568593465 startingPage "e0169466" @default.
• W2568593465 abstract "Prompt identification of bloodstream pathogens is essential for optimal management of patients. Significant changes in analytical methods have improved the turnaround time for laboratory diagnosis. Less attention has been paid to the time elapsing from blood collection to incubation and to its potential effect on recovery of pathogens. We evaluated the performance of blood cultures collected under typical hospital conditions in relation to the length of their pre-analytical time.We carried out a large retrospective study including 50,955 blood cultures collected, over a 30-month period, from 7,035 adult septic patients. Cultures were accepted by the laboratory only during opening time (Mon-Fri: 8am-4pm; Sat: 8am-2pm). Samples collected outside laboratory hours were stored at room temperature at clinical wards. All cultures were processed by automated culture systems. Day and time of blood collection and of culture incubation were known for all samples.A maximum pre-analytical interval of 2 hours is recommended by guidelines. When the laboratory was open, 57% of cultures were processed within 2 h. When the laboratory was closed, 4.9% of cultures were processed within 2 h (P<0.001). Samples collected when the laboratory was closed showed pre-analytical times significantly longer than those collected when laboratory was open (median time: 13 h and 1 h, respectively, P<0.001). The prevalence of positive cultures was significantly lower for samples collected when the laboratory was closed compared to open (11% vs 13%, P<0.001). The probability of a positive result decreased of 16% when the laboratory was closed (OR:0.84; 95%CI:0.80-0.89, P<0.001). Further, each hour elapsed from blood collection to incubation resulted associated with a decrease of 0.3% (OR:0.997; 95%CI:0.994-0.999, P<0.001) in the probability of a positive result.Delayed insertions of cultures into automated systems was associated with lower detection rates, with potentially important consequences for patients. In each hospital setting the logistic factors able to shorten pre-analytical time should be carefully investigated and specifically targeted." @default.
• W2568593465 created "2017-01-13" @default.
• W2568593465 creator A5014800962 @default.
• W2568593465 creator A5017252534 @default.
• W2568593465 creator A5019537806 @default.
• W2568593465 creator A5060617281 @default.
• W2568593465 creator A5066376259 @default.
• W2568593465 creator A5073280348 @default.
• W2568593465 creator A5075209348 @default.
• W2568593465 creator A5082570595 @default.
• W2568593465 creator A5034060611 @default.
• W2568593465 date "2017-01-03" @default.
• W2568593465 modified "2023-10-14" @default.
• W2568593465 title "Impact of Pre-Analytical Time on the Recovery of Pathogens from Blood Cultures: Results from a Large Retrospective Survey" @default.
• W2568593465 cites W1495627663 @default.
• W2568593465 cites W1538461375 @default.
• W2568593465 cites W1540378682 @default.
• W2568593465 cites W1865549965 @default.
• W2568593465 cites W1954906669 @default.
• W2568593465 cites W1963547974 @default.
• W2568593465 cites W1968201304 @default.
• W2568593465 cites W1971665595 @default.
• W2568593465 cites W1973112713 @default.
• W2568593465 cites W2007829496 @default.
• W2568593465 cites W2012263137 @default.
• W2568593465 cites W2026209824 @default.
• W2568593465 cites W2046761665 @default.
• W2568593465 cites W2047442953 @default.
• W2568593465 cites W2059285307 @default.
• W2568593465 cites W2069439040 @default.
• W2568593465 cites W2073316020 @default.
• W2568593465 cites W2077788180 @default.
• W2568593465 cites W2096039005 @default.
• W2568593465 cites W2101365338 @default.
• W2568593465 cites W2107421688 @default.
• W2568593465 cites W2108668149 @default.
• W2568593465 cites W2110287850 @default.
• W2568593465 cites W2114335471 @default.
• W2568593465 cites W2118926217 @default.
• W2568593465 cites W2125280696 @default.
• W2568593465 cites W2129948110 @default.
• W2568593465 cites W2133609104 @default.
• W2568593465 cites W2144860848 @default.
• W2568593465 cites W2155860425 @default.
• W2568593465 cites W2168803508 @default.
• W2568593465 cites W2181262698 @default.
• W2568593465 cites W2351595000 @default.
• W2568593465 cites W2499911733 @default.
• W2568593465 cites W2581605534 @default.
• W2568593465 cites W3023757607 @default.
• W2568593465 doi "https://doi.org/10.1371/journal.pone.0169466" @default.
• W2568593465 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5207733" @default.
• W2568593465 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28046040" @default.
• W2568593465 hasPublicationYear "2017" @default.
• W2568593465 type Work @default.
• W2568593465 sameAs 2568593465 @default.
• W2568593465 citedByCount "27" @default.
• W2568593465 countsByYear W25685934652018 @default.
• W2568593465 countsByYear W25685934652019 @default.
• W2568593465 countsByYear W25685934652020 @default.
• W2568593465 countsByYear W25685934652021 @default.
• W2568593465 countsByYear W25685934652022 @default.
• W2568593465 countsByYear W25685934652023 @default.
• W2568593465 crossrefType "journal-article" @default.
• W2568593465 hasAuthorship W2568593465A5014800962 @default.
• W2568593465 hasAuthorship W2568593465A5017252534 @default.
• W2568593465 hasAuthorship W2568593465A5019537806 @default.
• W2568593465 hasAuthorship W2568593465A5034060611 @default.
• W2568593465 hasAuthorship W2568593465A5060617281 @default.
• W2568593465 hasAuthorship W2568593465A5066376259 @default.
• W2568593465 hasAuthorship W2568593465A5073280348 @default.
• W2568593465 hasAuthorship W2568593465A5075209348 @default.
• W2568593465 hasAuthorship W2568593465A5082570595 @default.
• W2568593465 hasBestOaLocation W25685934651 @default.
• W2568593465 hasConcept C111919701 @default.
• W2568593465 hasConcept C126322002 @default.
• W2568593465 hasConcept C143701427 @default.
• W2568593465 hasConcept C167135981 @default.
• W2568593465 hasConcept C176553487 @default.
• W2568593465 hasConcept C194828623 @default.
• W2568593465 hasConcept C25642318 @default.
• W2568593465 hasConcept C2779473907 @default.
• W2568593465 hasConcept C2994091943 @default.
• W2568593465 hasConcept C41008148 @default.
• W2568593465 hasConcept C42972112 @default.
• W2568593465 hasConcept C501593827 @default.
• W2568593465 hasConcept C55493867 @default.
• W2568593465 hasConcept C71924100 @default.
• W2568593465 hasConcept C86803240 @default.
• W2568593465 hasConcept C89423630 @default.
• W2568593465 hasConceptScore W2568593465C111919701 @default.
• W2568593465 hasConceptScore W2568593465C126322002 @default.
• W2568593465 hasConceptScore W2568593465C143701427 @default.
• W2568593465 hasConceptScore W2568593465C167135981 @default.
• W2568593465 hasConceptScore W2568593465C176553487 @default.
• W2568593465 hasConceptScore W2568593465C194828623 @default.
• W2568593465 hasConceptScore W2568593465C25642318 @default.
• W2568593465 hasConceptScore W2568593465C2779473907 @default.

• next