FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2568875246> ?p ?o ?g. }

• W2568875246 endingPage "99" @default.
• W2568875246 startingPage "90" @default.
• W2568875246 abstract "Phenotypic overlap between the two main chronic airway pulmonary diseases, asthma and chronic obstructive pulmonary disease (COPD), has been the subject of debate for decades, and recently the nomenclature of asthma-COPD overlap syndrome (ACOS) was adopted for this condition. The definition of this entity in the literature is, however, very heterogeneous, it is therefore important to define how it applies to Portugal. A literature review of ACOS was made in a first phase resulting in the drawing up of a document that was later submitted for discussion among a panel of chronic lung diseases experts, resulting in reflexions about diagnosis, treatment and clinical guidance for ACOS patients. There was a consensus among the experts that the diagnosis of ACOS should be considered in the concomitant presence of: clinical manifestations characteristic of both asthma and COPD, persistent airway obstruction (post-bronchodilator FEV1/FVC < 0.7), positive response to bronchodilator test (increase in FEV1 of ≥200 mL and ≥12% from baseline) and current or past history of smoking or biomass exposure. In reaching diagnosis, the presence of peripheral eosinophilia (>300 eosinophils/μL or >5% of leukocytes) and previous history of atopy should also be considered. The recommended first line pharmacological treatment in these patients is the ICS/LABA association; if symptomatic control is not achieved or in case of clinical severity, triple therapy with ICS/LABA/LAMA may be used. An effective control of the exposure to risk factors, vaccination, respiratory rehabilitation and treatment of comorbidities is also important. The creation of initial guidelines on ACOS, which can be applied in the Portuguese context, has an important role in the generation of a broad nationwide consensus. This will give, in the near future, a far better clinical, functional and epidemiological characterization of ACOS patients, with the ultimate goal of achieving better therapeutic guidance." @default.
• W2568875246 created "2017-01-13" @default.
• W2568875246 creator A5000145197 @default.
• W2568875246 creator A5017255739 @default.
• W2568875246 creator A5018480203 @default.
• W2568875246 creator A5032160358 @default.
• W2568875246 creator A5049150878 @default.
• W2568875246 creator A5080637135 @default.
• W2568875246 creator A5083912647 @default.
• W2568875246 creator A5084592347 @default.
• W2568875246 date "2017-03-01" @default.
• W2568875246 modified "2023-10-02" @default.
• W2568875246 title "Asthma-chronic obstructive pulmonary disease overlap syndrome – Literature review and contributions towards a Portuguese consensus" @default.
• W2568875246 cites W1225175389 @default.
• W2568875246 cites W1535443304 @default.
• W2568875246 cites W1760281680 @default.
• W2568875246 cites W1799595710 @default.
• W2568875246 cites W1834761887 @default.
• W2568875246 cites W1863942808 @default.
• W2568875246 cites W1881393816 @default.
• W2568875246 cites W1908672337 @default.
• W2568875246 cites W1933728871 @default.
• W2568875246 cites W1947647143 @default.
• W2568875246 cites W1968859882 @default.
• W2568875246 cites W1972063938 @default.
• W2568875246 cites W1973172923 @default.
• W2568875246 cites W1986142113 @default.
• W2568875246 cites W2004783173 @default.
• W2568875246 cites W2004871449 @default.
• W2568875246 cites W2024949965 @default.
• W2568875246 cites W2056032598 @default.
• W2568875246 cites W2056770521 @default.
• W2568875246 cites W2059718063 @default.
• W2568875246 cites W2064900374 @default.
• W2568875246 cites W2066889593 @default.
• W2568875246 cites W2067545694 @default.
• W2568875246 cites W2068341684 @default.
• W2568875246 cites W2068659223 @default.
• W2568875246 cites W2072845909 @default.
• W2568875246 cites W2082185102 @default.
• W2568875246 cites W2085819077 @default.
• W2568875246 cites W2092406987 @default.
• W2568875246 cites W2099088996 @default.
• W2568875246 cites W2099676542 @default.
• W2568875246 cites W2109006492 @default.
• W2568875246 cites W2109815195 @default.
• W2568875246 cites W2111324648 @default.
• W2568875246 cites W2111608431 @default.
• W2568875246 cites W2112503036 @default.
• W2568875246 cites W2113430717 @default.
• W2568875246 cites W2114472469 @default.
• W2568875246 cites W2115232380 @default.
• W2568875246 cites W2117331512 @default.
• W2568875246 cites W2121680717 @default.
• W2568875246 cites W2122616097 @default.
• W2568875246 cites W2122819603 @default.
• W2568875246 cites W2124006946 @default.
• W2568875246 cites W2130049277 @default.
• W2568875246 cites W2130735124 @default.
• W2568875246 cites W2131330120 @default.
• W2568875246 cites W2133599193 @default.
• W2568875246 cites W2135622170 @default.
• W2568875246 cites W2135772522 @default.
• W2568875246 cites W2136612906 @default.
• W2568875246 cites W2138148311 @default.
• W2568875246 cites W2140694080 @default.
• W2568875246 cites W2142519704 @default.
• W2568875246 cites W2142838785 @default.
• W2568875246 cites W2147138578 @default.
• W2568875246 cites W2151061913 @default.
• W2568875246 cites W2152569940 @default.
• W2568875246 cites W2153322953 @default.
• W2568875246 cites W2155767904 @default.
• W2568875246 cites W2156400407 @default.
• W2568875246 cites W2157327311 @default.
• W2568875246 cites W2157372380 @default.
• W2568875246 cites W2157925125 @default.
• W2568875246 cites W2159219764 @default.
• W2568875246 cites W2159897450 @default.
• W2568875246 cites W2160994264 @default.
• W2568875246 cites W2164158986 @default.
• W2568875246 cites W2167574236 @default.
• W2568875246 cites W2177222627 @default.
• W2568875246 cites W2195424142 @default.
• W2568875246 cites W2225620279 @default.
• W2568875246 cites W2257757296 @default.
• W2568875246 cites W2300140420 @default.
• W2568875246 cites W2333559685 @default.
• W2568875246 cites W2344461732 @default.
• W2568875246 cites W2345700808 @default.
• W2568875246 cites W2403219962 @default.
• W2568875246 cites W2417667850 @default.
• W2568875246 cites W2462668116 @default.
• W2568875246 doi "https://doi.org/10.1016/j.rppnen.2016.11.005" @default.
• W2568875246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28089081" @default.
• W2568875246 hasPublicationYear "2017" @default.
• W2568875246 type Work @default.
• W2568875246 sameAs 2568875246 @default.

• next