FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2569258052> ?p ?o ?g. }

• W2569258052 abstract "Heparin saline (HS) is theoretically superior to normal saline (NS) for maintaining the patency of central venous catheters (CVCs), but the comparative efficacy of them remains controversial. The aim of this systematic review and meta-analysis was to assess the efficacy of NS versus HS in the maintenance of the patency of CVCs in adult patients. We searched PubMed, Embase and the Cochrane library databases. Randomized controlled trials (RCTs) evaluating the use of NS vs. HS to maintain the permeability of CVCs among adult patients were included in our meta-analysis. References of relevant papers were reviewed manually. No language restriction was applied. Non-human studies were excluded. Pooled relative risk (RR) was calculated using a Mantel-Haenszel random-effects model. We also performed subgroup analysis examining the effect of the duration of catheter placement on the outcome. All statistical tests were two-sided using a significance level of 0.05. Ten RCTs involving 7875 subjects (with analysis at patient, catheter, lumen and line access level) were included in this meta-analysis. Whether in terms of pooled or local analysis (RR with 95% confidence interval spans 1), NS can be equally, if not more effective, in keeping the CVCs open. Of studies reporting secondary outcomes (maneuver needed, heparin-induced thrombocytopenia, haemorrhage, central venous thrombosis and catheter-related bloodstream infection), heparinised saline was shown not to be superior to non-heparinised solution. Subgroup analysis in patients with short vs long term CVC placement was consistent with the main outcome partly and in particular for maintenance of catheter patency in patients with a long-term placement i.e. >30 days, the RR was 0.97 (n = 6589; 95% CI = 0.76 to 1.23; P = 0.796). However, for patients in whom the catheter was in place for <30 days, the RR was 1.52 (n = 1286; 95% CI = 1.02 to 2.27; P = 0.041). Based on the results of this meta-analysis, HS is not superior to NS in reducing CVCs occlusion. But in the short term, the use of HS is slightly superior to NS for flushing catheters from a statistical point of view." @default.
• W2569258052 created "2017-01-13" @default.
• W2569258052 creator A5001260755 @default.
• W2569258052 creator A5020071622 @default.
• W2569258052 creator A5036266768 @default.
• W2569258052 creator A5049477911 @default.
• W2569258052 creator A5052780622 @default.
• W2569258052 creator A5064940993 @default.
• W2569258052 creator A5065236570 @default.
• W2569258052 creator A5073783845 @default.
• W2569258052 creator A5089118003 @default.
• W2569258052 date "2017-01-08" @default.
• W2569258052 modified "2023-10-10" @default.
• W2569258052 title "Normal saline versus heparin for patency of central venous catheters in adult patients - a systematic review and meta-analysis" @default.
• W2569258052 cites W1547290897 @default.
• W2569258052 cites W1598602811 @default.
• W2569258052 cites W1877658191 @default.
• W2569258052 cites W1931146984 @default.
• W2569258052 cites W1969101733 @default.
• W2569258052 cites W1973369259 @default.
• W2569258052 cites W1985667424 @default.
• W2569258052 cites W1989262947 @default.
• W2569258052 cites W1991448387 @default.
• W2569258052 cites W1995592979 @default.
• W2569258052 cites W2010438101 @default.
• W2569258052 cites W2020815942 @default.
• W2569258052 cites W2037552682 @default.
• W2569258052 cites W2044766576 @default.
• W2569258052 cites W2050477557 @default.
• W2569258052 cites W2051106992 @default.
• W2569258052 cites W2061991526 @default.
• W2569258052 cites W2073102298 @default.
• W2569258052 cites W2103474881 @default.
• W2569258052 cites W2106253436 @default.
• W2569258052 cites W2107726086 @default.
• W2569258052 cites W2109887283 @default.
• W2569258052 cites W2112366983 @default.
• W2569258052 cites W2125435699 @default.
• W2569258052 cites W2130467619 @default.
• W2569258052 cites W2130888802 @default.
• W2569258052 cites W2131972531 @default.
• W2569258052 cites W2133350862 @default.
• W2569258052 cites W2136123911 @default.
• W2569258052 cites W2140146599 @default.
• W2569258052 cites W2156098321 @default.
• W2569258052 cites W2157033333 @default.
• W2569258052 cites W2157823046 @default.
• W2569258052 cites W2163967334 @default.
• W2569258052 cites W2188117168 @default.
• W2569258052 cites W2292122125 @default.
• W2569258052 cites W2314818861 @default.
• W2569258052 cites W2321356931 @default.
• W2569258052 cites W2991792334 @default.
• W2569258052 cites W4210992029 @default.
• W2569258052 doi "https://doi.org/10.1186/s13054-016-1585-x" @default.
• W2569258052 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5219914" @default.
• W2569258052 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28063456" @default.
• W2569258052 hasPublicationYear "2017" @default.
• W2569258052 type Work @default.
• W2569258052 sameAs 2569258052 @default.
• W2569258052 citedByCount "41" @default.
• W2569258052 countsByYear W25692580522017 @default.
• W2569258052 countsByYear W25692580522018 @default.
• W2569258052 countsByYear W25692580522019 @default.
• W2569258052 countsByYear W25692580522020 @default.
• W2569258052 countsByYear W25692580522021 @default.
• W2569258052 countsByYear W25692580522022 @default.
• W2569258052 countsByYear W25692580522023 @default.
• W2569258052 crossrefType "journal-article" @default.
• W2569258052 hasAuthorship W2569258052A5001260755 @default.
• W2569258052 hasAuthorship W2569258052A5020071622 @default.
• W2569258052 hasAuthorship W2569258052A5036266768 @default.
• W2569258052 hasAuthorship W2569258052A5049477911 @default.
• W2569258052 hasAuthorship W2569258052A5052780622 @default.
• W2569258052 hasAuthorship W2569258052A5064940993 @default.
• W2569258052 hasAuthorship W2569258052A5065236570 @default.
• W2569258052 hasAuthorship W2569258052A5073783845 @default.
• W2569258052 hasAuthorship W2569258052A5089118003 @default.
• W2569258052 hasBestOaLocation W25692580521 @default.
• W2569258052 hasConcept C126322002 @default.
• W2569258052 hasConcept C141071460 @default.
• W2569258052 hasConcept C168563851 @default.
• W2569258052 hasConcept C187960798 @default.
• W2569258052 hasConcept C2776478404 @default.
• W2569258052 hasConcept C2777397205 @default.
• W2569258052 hasConcept C2777557582 @default.
• W2569258052 hasConcept C2778446481 @default.
• W2569258052 hasConcept C2780011451 @default.
• W2569258052 hasConcept C2780868729 @default.
• W2569258052 hasConcept C2781267111 @default.
• W2569258052 hasConcept C42219234 @default.
• W2569258052 hasConcept C44249647 @default.
• W2569258052 hasConcept C71924100 @default.
• W2569258052 hasConcept C78221805 @default.
• W2569258052 hasConcept C82789193 @default.
• W2569258052 hasConcept C95190672 @default.
• W2569258052 hasConceptScore W2569258052C126322002 @default.
• W2569258052 hasConceptScore W2569258052C141071460 @default.
• W2569258052 hasConceptScore W2569258052C168563851 @default.
• W2569258052 hasConceptScore W2569258052C187960798 @default.

• next