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- W2569475347 abstract "Purpose Neuroimaging studies provide vital information related to the neurobiology of ADHD, but there still exists a wide gap in relevant information. The present study aimed to elucidate the neuroanatomical alteration in Attention deficit hyperactivity disorder (ADHD) children/adolescents. Methods Voxel-based cortical thickness (VBCT) and voxel-based morphometry (VBM) was performed to examine neuroanatomic distinctions in 18 children/adolescents aged 7.5–13 years diagnosed with DSM-IV TR as ADHD (non-medicated). They were compared with 18 healthy matched controls. Results VBCT findings in ADHD children/adolescents revealed reduced cortical thickness in the left superior frontal, left orbito-frontal and left dorsal anterior cingulate cortex. VBM findings confirmed decreased gray matter volume in the left orbito frontal, left middle frontal/dorsolateral prefrontal, left middle temporal and left cerebellum in comparison to control group. A decrease in white matter volume was also observed in the left inferior frontal and left calcarine of ADHD children/adolescents. Conclusion Results reflect possible abnormal neuroanatomical development patterns in ADHD children." @default.
- W2569475347 created "2017-01-13" @default.
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- W2569475347 date "2017-05-01" @default.
- W2569475347 modified "2023-10-18" @default.
- W2569475347 title "Neural alterations in ADHD children as indicated by voxel-based cortical thickness and morphometry analysis" @default.
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- W2569475347 doi "https://doi.org/10.1016/j.braindev.2016.12.002" @default.
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