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- W2569525025 abstract "The gut microbiota plays a pivotal role in the onset of pouchitis in ulcerative colitis patients after restorative proctocolectomy with ileal pouch–anal anastomosis. Hence, antibiotics are used widely to treat this condition. Probiotics may represent a valid and safer alternative. Controlled studies investigating the possible efficacy of probiotic agents in the treatment of active pouchitis are few and inconclusive so far. By contrast, the prophylactic use of probiotic mixtures, such as VSL#3 appears able to prevent development of pouchitis. The most striking results have been obtained in the maintenance of remission, where VSL#3 has been found, in most of the trials, effective in preventing recurrence of pouchitis." @default.
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- W2569525025 date "2017-01-01" @default.
- W2569525025 modified "2023-09-24" @default.
- W2569525025 title "Probiotics in the Treatment of Pouchitis" @default.
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- W2569525025 doi "https://doi.org/10.1016/b978-0-12-804024-9.00035-5" @default.
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