FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2569525113> ?p ?o ?g. }

• W2569525113 endingPage "3780" @default.
• W2569525113 startingPage "3774" @default.
• W2569525113 abstract ": There are certain well defined clinical situations where prolonged therapy is beneficial, but prolonged duration of antibiotic therapy is associated with increased resistance, medicalising effects, high costs and adverse drug reactions. The best way to decrease antibiotic duration is both to stop antibiotics when not needed (sterile invasive cultures with clinical improvement), not to start antibiotics when not indicated (treating colonization) and keep the antibiotic course as short as possible. The optimal duration of antimicrobial treatment for ventilator-associated pneumonia (VAP) is unknown, however, there is a growing evidence that reduction in the length of antibiotic courses to 7–8 days can minimize the consequences of antibiotic overuse in critical care, including antibiotic resistance, adverse effects, collateral damage and costs. Biomarkers like C-reactive protein (CRP) and procalcitonin (PCT) do have a valuable role in helping guide antibiotic duration but should be interpreted cautiously in the context of the clinical situation. On the other hand, microbiological criteria alone are not reliable and should not be used to justify a prolonged antibiotic course, as clinical cure does not equate to microbiological eradication. We do not recommend a ‘one size fits all’ approach and in some clinical situations, including infection with non-fermenting Gram-negative bacilli (NF-GNB) clinical evaluation is needed but shortening the antibiotic course is an effective and safe way to decrease inappropriate antibiotic exposure." @default.
• W2569525113 created "2017-01-13" @default.
• W2569525113 creator A5000894127 @default.
• W2569525113 creator A5034004394 @default.
• W2569525113 creator A5040244754 @default.
• W2569525113 creator A5062287721 @default.
• W2569525113 date "2016-12-01" @default.
• W2569525113 modified "2023-10-06" @default.
• W2569525113 title "Duration of antibiotic therapy in the intensive care unit" @default.
• W2569525113 cites W1631673730 @default.
• W2569525113 cites W1853354004 @default.
• W2569525113 cites W1916342366 @default.
• W2569525113 cites W1957333351 @default.
• W2569525113 cites W1975477886 @default.
• W2569525113 cites W1981332539 @default.
• W2569525113 cites W1983957285 @default.
• W2569525113 cites W1998996093 @default.
• W2569525113 cites W2033541705 @default.
• W2569525113 cites W2039181347 @default.
• W2569525113 cites W2050709114 @default.
• W2569525113 cites W2055656378 @default.
• W2569525113 cites W2079018559 @default.
• W2569525113 cites W2098422452 @default.
• W2569525113 cites W2100154890 @default.
• W2569525113 cites W2105436245 @default.
• W2569525113 cites W2110521392 @default.
• W2569525113 cites W2133894066 @default.
• W2569525113 cites W2144232597 @default.
• W2569525113 cites W2146470820 @default.
• W2569525113 cites W2150498285 @default.
• W2569525113 cites W2158031792 @default.
• W2569525113 cites W2160739269 @default.
• W2569525113 cites W2162970450 @default.
• W2569525113 cites W2164871906 @default.
• W2569525113 cites W2165760729 @default.
• W2569525113 cites W2166061684 @default.
• W2569525113 cites W2166822894 @default.
• W2569525113 cites W2473016454 @default.
• W2569525113 cites W2528337832 @default.
• W2569525113 cites W4242185466 @default.
• W2569525113 cites W4244930730 @default.
• W2569525113 cites W4249764287 @default.
• W2569525113 doi "https://doi.org/10.21037/jtd.2016.12.89" @default.
• W2569525113 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5227227" @default.
• W2569525113 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28149576" @default.
• W2569525113 hasPublicationYear "2016" @default.
• W2569525113 type Work @default.
• W2569525113 sameAs 2569525113 @default.
• W2569525113 citedByCount "51" @default.
• W2569525113 countsByYear W25695251132017 @default.
• W2569525113 countsByYear W25695251132018 @default.
• W2569525113 countsByYear W25695251132019 @default.
• W2569525113 countsByYear W25695251132020 @default.
• W2569525113 countsByYear W25695251132021 @default.
• W2569525113 countsByYear W25695251132022 @default.
• W2569525113 countsByYear W25695251132023 @default.
• W2569525113 crossrefType "journal-article" @default.
• W2569525113 hasAuthorship W2569525113A5000894127 @default.
• W2569525113 hasAuthorship W2569525113A5034004394 @default.
• W2569525113 hasAuthorship W2569525113A5040244754 @default.
• W2569525113 hasAuthorship W2569525113A5062287721 @default.
• W2569525113 hasBestOaLocation W25695251132 @default.
• W2569525113 hasConcept C10936531 @default.
• W2569525113 hasConcept C126322002 @default.
• W2569525113 hasConcept C151730666 @default.
• W2569525113 hasConcept C177713679 @default.
• W2569525113 hasConcept C197934379 @default.
• W2569525113 hasConcept C2776376669 @default.
• W2569525113 hasConcept C2777184939 @default.
• W2569525113 hasConcept C2777914695 @default.
• W2569525113 hasConcept C2778384902 @default.
• W2569525113 hasConcept C2779343474 @default.
• W2569525113 hasConcept C2993328841 @default.
• W2569525113 hasConcept C4937899 @default.
• W2569525113 hasConcept C501593827 @default.
• W2569525113 hasConcept C71924100 @default.
• W2569525113 hasConcept C86803240 @default.
• W2569525113 hasConcept C89423630 @default.
• W2569525113 hasConcept C94665300 @default.
• W2569525113 hasConceptScore W2569525113C10936531 @default.
• W2569525113 hasConceptScore W2569525113C126322002 @default.
• W2569525113 hasConceptScore W2569525113C151730666 @default.
• W2569525113 hasConceptScore W2569525113C177713679 @default.
• W2569525113 hasConceptScore W2569525113C197934379 @default.
• W2569525113 hasConceptScore W2569525113C2776376669 @default.
• W2569525113 hasConceptScore W2569525113C2777184939 @default.
• W2569525113 hasConceptScore W2569525113C2777914695 @default.
• W2569525113 hasConceptScore W2569525113C2778384902 @default.
• W2569525113 hasConceptScore W2569525113C2779343474 @default.
• W2569525113 hasConceptScore W2569525113C2993328841 @default.
• W2569525113 hasConceptScore W2569525113C4937899 @default.
• W2569525113 hasConceptScore W2569525113C501593827 @default.
• W2569525113 hasConceptScore W2569525113C71924100 @default.
• W2569525113 hasConceptScore W2569525113C86803240 @default.
• W2569525113 hasConceptScore W2569525113C89423630 @default.
• W2569525113 hasConceptScore W2569525113C94665300 @default.
• W2569525113 hasIssue "12" @default.
• W2569525113 hasLocation W25695251131 @default.

• next