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- W2569529245 abstract "Context: Quantitative changes of salivary proteins due to acute stress were detected.Objective: To explore protein markers of stress in saliva of eight medical residents who performed emergency medicine simulations.Materials and methods: Saliva was collected before the simulations, after the simulations, and following morning upon waking. Proteins were separated by sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE), identified by mass spectrometry (MS), and relatively quantified by densitometry.Results: Salivary alpha-amylase and S–type cystatins significantly increased, while the ∼26 kDa and low-molecular weight (MW) (<10 kDa) SDS-PAGE bands exhibited changes after stress.Discussion and conclusion: Alpha-amylase and cystatins are potential salivary markers of acute stress, but further validation should be performed using larger sample populations." @default.
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- W2569529245 date "2017-01-25" @default.
- W2569529245 modified "2023-10-16" @default.
- W2569529245 title "Salivary protein changes in response to acute stress in medical residents performing advanced clinical simulations: a pilot proteomics study" @default.
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- W2569529245 doi "https://doi.org/10.1080/1354750x.2017.1279215" @default.
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