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- W2569718957 abstract "Objective: To investigate the clinical efficacy of the addition of a triple pulsed, 755-nm filtered flashlamp intense pulsed light to a single-pass 560-nm filter for the treatment of facial rhytids and other aspects of photodamage. Design: A single-center, prospective, randomized, phase 4 split-face clinical trial. Methods: Twenty female volunteers with Fitzpatrick skin type I–IV with a Rao-Goldman wrinkle score of 2 or higher received 2 split-face treatments 4 weeks apart, in which half of the face was treated with 1 pass of a double-pulsed 560-nm filter and the other half was treated with a double-pulsed 560-nm filter followed by a triple-pulsed 755-nm filtered nonablative intense pulsed light. Fluence varied from 15–19 J/cm 2 . Efficacy was evaluated by patient self-assessments and by blinded clinical and photographic evaluations 1 month after the final treatment. Adverse effects were assessed clinically. Results: All patients noted improvement in pigmentation on both sides of the face, and 60% of patients noted an improvement in skin texture on the side that received the 755-nm filter; however, there was no discernable difference in rhytid reduction between the 560 + 755 filtered side compared with the 560 filtered side alone. Discussion: Two split-face intense pulsed light treatments delivered 4 weeks apart with half of the face receiving double-pulsed 560 filter treatment and the other half receiving a double-pulsed 560 filter + triple-pulsed 755 filter treatment showed no improvement in rhytid reduction. There was a subjective improvement in texture and pore size noted by patients on the side treated with the 560 + 755-nm filtered intense pulsed light treatment." @default.
- W2569718957 created "2017-01-13" @default.
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- W2569718957 date "2007-12-01" @default.
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- W2569718957 title "Single-Center, Prospective, Randomized, Phase 4 Clinical Trial to Determine the Effects of Single-Pass 560-nm Filter Intense Pulsed Light with or without an Additional Pass with a 755-nm Filter for the Reduction of Facial Rhytides" @default.
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- W2569718957 doi "https://doi.org/10.1177/074880680702400402" @default.
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