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- W2569736706 abstract "We previously reported that the infusion and the methanol extract from the aerial parts of Hypericum reflexum L. fil., an endemic species of the Canary Islands, showed antidepressant activity in mice [1, 2]. Preliminary phytochemical analysis carried out with the methanol extract of this species reveals the presence of flavonoids, tannins, saponins and anthraquinones. The presence of hypericin could not be detected in the crude methanol extract. On the basis of these results, the present study was undertaken to evaluate the antidepressant activity of the aqueous, butanol and chloroform fractions obtained from the methanol extract of this plant on the forced swimming test in mice. Also the effects of these fractions on locomotor activity, body temperature and sleep potentiation were evaluated. Student's t-test was used to verify the statistical significance." @default.
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- W2569736706 date "2006-08-24" @default.
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- W2569736706 title "Effects of some Hypericum reflexum L. fil. extracts in the forced swimming test in mice" @default.
- W2569736706 doi "https://doi.org/10.1055/s-2006-950025" @default.
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