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- W2570255826 abstract "Oxidative stress and cellular excitotoxicity is inherent in the pathophysiology of an array of devastating human ailments. Natural products have played an important role in the treatment of a variety of human diseases and continue to drive the modern drug discovery and development process. The overall goal of this project is to design a novel neuroactivity assay to identify natural products capable of inducing neuroprotection against oxidative stress. This project will focus on a group of natural products, pseudopterosins, known for their potent biological activities with a novel mechanism of action. We hypothesize that these compounds may be of potential therapeutic benefit in protecting neurons and/or neural function both during and after episodes of excitotoxicity in disease states." @default.
- W2570255826 created "2017-01-13" @default.
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- W2570255826 date "2015-06-25" @default.
- W2570255826 modified "2023-10-18" @default.
- W2570255826 title "Discovery of neuroprotective marine natural products using Drosophila melanogaster" @default.
- W2570255826 doi "https://doi.org/10.1055/s-0035-1556425" @default.
- W2570255826 hasPublicationYear "2015" @default.
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