Matches in SemOpenAlex for { <https://semopenalex.org/work/W2570319749> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2570319749 abstract "Objective: Our aim is to investigate relationship between matrix metalloproteinases (MMPs) and dolichoectasia of carotid artery. Background: DE prevalence among individuals with stroke has been reported between 3,1 [percnt] in a population based sample. MMP dysregulation and other predisposing genetic factor related to collagen, elastin or ECM health are associated with DE. MMPs are enzymes suggested as a possible candidate for pathogenesis of arterial dilatation.Metods: We selected 70 subjects for the study group among patients admitted to radiology unite with any symptoms in order to be taken CT angiography between 2014 March -2015 January. On CT angiography aneurysms, artery dissections, AV malformations and other vascular pathologies and carotid artery stenosis including non-significant stenosis were excluded. Only DE in cervical and/or intracranial carotid artery was included. 18 patients for control group were chosen from patients admitted to neurology outpatient clinic with headache and/or vertigo and who had normal CT and/or MR angiography. We investigated serum MMP 1, 2, 3, 12 levels in extracranial and intracranial carotid DE. Atherosclerosis and other vascular risk factors were also noted for all patients.Results: Among vascular risk factors; HT, DM were more common in kink group than control group and there were significant difference between them(p=0.0011 and p=0.020). MMP-2 levels were significantly higher in kink and tortuous group than control group (p=0.001 and p=0.000). In study group; MMP-12 levels were also significantly higher in patients with atheromatous plaques than without plaques (p=0.020).Conclusions: MMP-2 may play a role in the etiology of DE or kink /tortuosity of carotid artery may cause elevation of MMP-2 in plasma. MMP-12 levels increases in carotid atherosclerotic lesions and may lead plaque formation. In future, MMP inhibitor therapies may appear to be a choice for the treatment of atherosclerotic plaques or DE. Disclosure: Dr. Arslan has nothing to disclose. Dr. Arslan has nothing to disclose. Dr. Pekcevik has nothing to disclose. Dr. Sener has nothing to disclose. Dr. Kose has nothing to disclose. Dr. Zorlu has nothing to disclose." @default.
- W2570319749 created "2017-01-13" @default.
- W2570319749 creator A5011797870 @default.
- W2570319749 creator A5042378000 @default.
- W2570319749 creator A5044261087 @default.
- W2570319749 creator A5067806335 @default.
- W2570319749 creator A5073741370 @default.
- W2570319749 creator A5083452679 @default.
- W2570319749 date "2016-04-05" @default.
- W2570319749 modified "2023-09-22" @default.
- W2570319749 title "Matrix Metalloproteinase Levels in Cervical and Intracranial Carotid Dolichoarteriopathies (P4.371)" @default.
- W2570319749 hasPublicationYear "2016" @default.
- W2570319749 type Work @default.
- W2570319749 sameAs 2570319749 @default.
- W2570319749 citedByCount "0" @default.
- W2570319749 crossrefType "journal-article" @default.
- W2570319749 hasAuthorship W2570319749A5011797870 @default.
- W2570319749 hasAuthorship W2570319749A5042378000 @default.
- W2570319749 hasAuthorship W2570319749A5044261087 @default.
- W2570319749 hasAuthorship W2570319749A5067806335 @default.
- W2570319749 hasAuthorship W2570319749A5073741370 @default.
- W2570319749 hasAuthorship W2570319749A5083452679 @default.
- W2570319749 hasConcept C118552586 @default.
- W2570319749 hasConcept C126322002 @default.
- W2570319749 hasConcept C127413603 @default.
- W2570319749 hasConcept C141071460 @default.
- W2570319749 hasConcept C142724271 @default.
- W2570319749 hasConcept C164705383 @default.
- W2570319749 hasConcept C16568411 @default.
- W2570319749 hasConcept C2779135839 @default.
- W2570319749 hasConcept C2779869378 @default.
- W2570319749 hasConcept C2780007028 @default.
- W2570319749 hasConcept C2780643987 @default.
- W2570319749 hasConcept C2780645631 @default.
- W2570319749 hasConcept C2780942790 @default.
- W2570319749 hasConcept C2781012200 @default.
- W2570319749 hasConcept C2908647359 @default.
- W2570319749 hasConcept C2910348082 @default.
- W2570319749 hasConcept C2987047532 @default.
- W2570319749 hasConcept C3020110884 @default.
- W2570319749 hasConcept C71924100 @default.
- W2570319749 hasConcept C78519656 @default.
- W2570319749 hasConcept C99454951 @default.
- W2570319749 hasConceptScore W2570319749C118552586 @default.
- W2570319749 hasConceptScore W2570319749C126322002 @default.
- W2570319749 hasConceptScore W2570319749C127413603 @default.
- W2570319749 hasConceptScore W2570319749C141071460 @default.
- W2570319749 hasConceptScore W2570319749C142724271 @default.
- W2570319749 hasConceptScore W2570319749C164705383 @default.
- W2570319749 hasConceptScore W2570319749C16568411 @default.
- W2570319749 hasConceptScore W2570319749C2779135839 @default.
- W2570319749 hasConceptScore W2570319749C2779869378 @default.
- W2570319749 hasConceptScore W2570319749C2780007028 @default.
- W2570319749 hasConceptScore W2570319749C2780643987 @default.
- W2570319749 hasConceptScore W2570319749C2780645631 @default.
- W2570319749 hasConceptScore W2570319749C2780942790 @default.
- W2570319749 hasConceptScore W2570319749C2781012200 @default.
- W2570319749 hasConceptScore W2570319749C2908647359 @default.
- W2570319749 hasConceptScore W2570319749C2910348082 @default.
- W2570319749 hasConceptScore W2570319749C2987047532 @default.
- W2570319749 hasConceptScore W2570319749C3020110884 @default.
- W2570319749 hasConceptScore W2570319749C71924100 @default.
- W2570319749 hasConceptScore W2570319749C78519656 @default.
- W2570319749 hasConceptScore W2570319749C99454951 @default.
- W2570319749 hasLocation W25703197491 @default.
- W2570319749 hasOpenAccess W2570319749 @default.
- W2570319749 hasPrimaryLocation W25703197491 @default.
- W2570319749 hasRelatedWork W1912555701 @default.
- W2570319749 hasRelatedWork W1964088875 @default.
- W2570319749 hasRelatedWork W2004319464 @default.
- W2570319749 hasRelatedWork W2149121518 @default.
- W2570319749 hasRelatedWork W2195273195 @default.
- W2570319749 hasRelatedWork W2358542331 @default.
- W2570319749 hasRelatedWork W2362472493 @default.
- W2570319749 hasRelatedWork W2375653617 @default.
- W2570319749 hasRelatedWork W2383265521 @default.
- W2570319749 hasRelatedWork W2390359356 @default.
- W2570319749 hasRelatedWork W2390423872 @default.
- W2570319749 hasRelatedWork W2407407915 @default.
- W2570319749 hasRelatedWork W2414420983 @default.
- W2570319749 hasRelatedWork W2466862129 @default.
- W2570319749 hasRelatedWork W2580669991 @default.
- W2570319749 hasRelatedWork W2997020055 @default.
- W2570319749 hasRelatedWork W2997375437 @default.
- W2570319749 hasRelatedWork W3205715906 @default.
- W2570319749 hasRelatedWork W646905684 @default.
- W2570319749 hasRelatedWork W3032281636 @default.
- W2570319749 hasVolume "86" @default.
- W2570319749 isParatext "false" @default.
- W2570319749 isRetracted "false" @default.
- W2570319749 magId "2570319749" @default.
- W2570319749 workType "article" @default.