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- W2570596471 abstract "Actinic keratosis is a precursor lesion to the most common nonmelanoma skin cancer. Conventional photodynamic therapy (PDT) has been shown to be effective, but the procedure is time-consuming, can be very painful, and requires infrastructure. These shortcomings led to the emergence of daylight PDT. To obtain a global estimate of efficacy, we undertook a systematic literature review and performed a meta-analysis of the available evidence on the efficacy and safety of daylight PDT as compared to conventional PDT in the treatment of actinic keratosis and/or field cancerization. The conclusion is that the difference in efficacy is clinically negligible (global estimate of the mean response rate difference, -3.69%; 95% CI, -6.54% to -0.84%). The adverse effects of daylight PDT are mild and localized (79% of patients report no discomfort), and patients report less pain (P<.001). Daylight PDT gives good to excellent cosmetic results in more than 90% of patients, and patient satisfaction is greater (P<.001)." @default.
- W2570596471 created "2017-01-13" @default.
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- W2570596471 date "2017-05-01" @default.
- W2570596471 modified "2023-10-17" @default.
- W2570596471 title "De la terapia fotodinámica convencional a la terapia fotodinámica con luz de día en el tratamiento de las queratosis actínicas: revisión sistemática y metaanálisis" @default.
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- W2570596471 doi "https://doi.org/10.1016/j.ad.2016.09.020" @default.
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