FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2570603605> ?p ?o ?g. }

• W2570603605 endingPage "10" @default.
• W2570603605 startingPage "1" @default.
• W2570603605 abstract "Given the potential savings in cost and resource utilization, several algorithms have been proposed to predict Oncotype DX recurrence score (ODX RS) using commonly acquired histopathologic variables. Although it is promising, additional independent validation of these surrogate markers is needed prior to guide the patient management.In this retrospective study, we analyzed 305 patients with invasive breast cancer at our institution who had ODX RS available. We selected five equations that provide a surrogate measure of ODX as previously published by Klein et al. (Magee equations 1-3), Gage et al., and Tang et al. All equations used estrogen receptor status and progesterone receptor status along with different combinations of grade, proliferation indices (Ki-67, mitotic rate), HER2 status, and tumor size.Of all surrogate scores tested, the Magee equation 2 provided the highest correlation with ODX both with regard to raw score (Pearson's correlation coefficient = 0.66 95% CI 0.59-0.72) and categorical correlation (Cohen's kappa = 0.43, 95% CI 0.33-0.53). Although Magee equation 2 provided a way to reliably identify high-risk disease by assigning 95% of the patients with high ODX RS to either the intermediate- or high-risk group, it was unable to reliably identify the potential for patients to have intermediate- or high-risk disease by ODX (66% of such patients identified).Although commonly available surrogates for ODX appear to predict high-risk ODX RS, they are unable to reliably rule out the presence of patients with intermediate-risk disease by ODX. Given the potential benefit of adjuvant chemotherapy in women with intermediate-risk disease by ODX, current surrogates are unable to safely substitute for ODX. Characterizing the true recurrence risk in patients with intermediate-risk disease by ODX is critical to the clinical adoption of current surrogate markers and is an area of ongoing clinical trials." @default.
• W2570603605 created "2017-01-13" @default.
• W2570603605 creator A5001300575 @default.
• W2570603605 creator A5005726073 @default.
• W2570603605 creator A5023835104 @default.
• W2570603605 creator A5032566475 @default.
• W2570603605 creator A5054599006 @default.
• W2570603605 creator A5089674277 @default.
• W2570603605 creator A5090984331 @default.
• W2570603605 date "2017-01-07" @default.
• W2570603605 modified "2023-10-16" @default.
• W2570603605 title "Algorithms for prediction of the Oncotype DX recurrence score using clinicopathologic data: a review and comparison using an independent dataset" @default.
• W2570603605 cites W1589403420 @default.
• W2570603605 cites W1990364400 @default.
• W2570603605 cites W1996392647 @default.
• W2570603605 cites W2008213731 @default.
• W2570603605 cites W2022767256 @default.
• W2570603605 cites W2026368827 @default.
• W2570603605 cites W2043409879 @default.
• W2570603605 cites W2044702943 @default.
• W2570603605 cites W2053741141 @default.
• W2570603605 cites W2058285642 @default.
• W2570603605 cites W2059272061 @default.
• W2570603605 cites W2080798207 @default.
• W2570603605 cites W2082326948 @default.
• W2570603605 cites W2099335989 @default.
• W2570603605 cites W2104792473 @default.
• W2570603605 cites W2105882193 @default.
• W2570603605 cites W2119975486 @default.
• W2570603605 cites W2125702566 @default.
• W2570603605 cites W2127057139 @default.
• W2570603605 cites W2128678633 @default.
• W2570603605 cites W2130900820 @default.
• W2570603605 cites W2136655134 @default.
• W2570603605 cites W2137853125 @default.
• W2570603605 cites W2158169271 @default.
• W2570603605 cites W2159443243 @default.
• W2570603605 cites W2160377567 @default.
• W2570603605 cites W2166357656 @default.
• W2570603605 cites W2172137105 @default.
• W2570603605 cites W2173858545 @default.
• W2570603605 cites W4255398094 @default.
• W2570603605 cites W4300591737 @default.
• W2570603605 doi "https://doi.org/10.1007/s10549-016-4093-4" @default.
• W2570603605 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5909985" @default.
• W2570603605 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28064383" @default.
• W2570603605 hasPublicationYear "2017" @default.
• W2570603605 type Work @default.
• W2570603605 sameAs 2570603605 @default.
• W2570603605 citedByCount "29" @default.
• W2570603605 countsByYear W25706036052017 @default.
• W2570603605 countsByYear W25706036052018 @default.
• W2570603605 countsByYear W25706036052019 @default.
• W2570603605 countsByYear W25706036052020 @default.
• W2570603605 countsByYear W25706036052021 @default.
• W2570603605 countsByYear W25706036052022 @default.
• W2570603605 crossrefType "journal-article" @default.
• W2570603605 hasAuthorship W2570603605A5001300575 @default.
• W2570603605 hasAuthorship W2570603605A5005726073 @default.
• W2570603605 hasAuthorship W2570603605A5023835104 @default.
• W2570603605 hasAuthorship W2570603605A5032566475 @default.
• W2570603605 hasAuthorship W2570603605A5054599006 @default.
• W2570603605 hasAuthorship W2570603605A5089674277 @default.
• W2570603605 hasAuthorship W2570603605A5090984331 @default.
• W2570603605 hasBestOaLocation W25706036052 @default.
• W2570603605 hasConcept C105795698 @default.
• W2570603605 hasConcept C117220453 @default.
• W2570603605 hasConcept C121608353 @default.
• W2570603605 hasConcept C126322002 @default.
• W2570603605 hasConcept C143998085 @default.
• W2570603605 hasConcept C2524010 @default.
• W2570603605 hasConcept C2778724333 @default.
• W2570603605 hasConcept C2779134260 @default.
• W2570603605 hasConcept C33923547 @default.
• W2570603605 hasConcept C530470458 @default.
• W2570603605 hasConcept C71924100 @default.
• W2570603605 hasConceptScore W2570603605C105795698 @default.
• W2570603605 hasConceptScore W2570603605C117220453 @default.
• W2570603605 hasConceptScore W2570603605C121608353 @default.
• W2570603605 hasConceptScore W2570603605C126322002 @default.
• W2570603605 hasConceptScore W2570603605C143998085 @default.
• W2570603605 hasConceptScore W2570603605C2524010 @default.
• W2570603605 hasConceptScore W2570603605C2778724333 @default.
• W2570603605 hasConceptScore W2570603605C2779134260 @default.
• W2570603605 hasConceptScore W2570603605C33923547 @default.
• W2570603605 hasConceptScore W2570603605C530470458 @default.
• W2570603605 hasConceptScore W2570603605C71924100 @default.
• W2570603605 hasFunder F4320308571 @default.
• W2570603605 hasFunder F4320332161 @default.
• W2570603605 hasIssue "1" @default.
• W2570603605 hasLocation W25706036051 @default.
• W2570603605 hasLocation W25706036052 @default.
• W2570603605 hasLocation W25706036053 @default.
• W2570603605 hasLocation W25706036054 @default.
• W2570603605 hasOpenAccess W2570603605 @default.
• W2570603605 hasPrimaryLocation W25706036051 @default.
• W2570603605 hasRelatedWork W2014447844 @default.
• W2570603605 hasRelatedWork W2113427382 @default.

• next