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• W2570662880 abstract "Musculoskeletal (MSK) symptoms in patients with systemic sclerosis (SSc) include articular involvement (arthralgia, synovitis, contractures), which is often an early phenomenon and significantly contributes to the disability. Predominantly the hands are affected. Consensus in outcome measures of articular involvement is missing. Health Assessment Questionnaire Disability Index (HAQ-DI), Cochin Hand Function Scale (CHFS), Hand Mobility Index in Scleroderma (HAMIS), and Disease Activity Score of 28 Joints (DAS28) may be used for the assessment of different aspects of joint involvement. There is an unmet need for therapies confirmed by randomized controlled clinical trials (RCTs) to treat both synovitis and non-inflammatory joint involvement. The few rehabilitation studies that have been conducted have shown some promising efficacy. Muscle involvement may be an early symptom. The presence of clinically meaningful muscle involvement often heralds an unfavourable prognosis. The histology of muscle biopsy shows a variable picture including inflammation and necrosis. Besides, signs of acute neurogenic atrophy have been recently described as a previously underestimated contributor to muscle weakness. Similar to articular involvement, the lack of classification criteria on inflammatory and non-inflammatory SSc-associated myopathies, and the lack of validated core set of outcome measures makes it difficult to perform RCTs. The SSc-specific fibrinous tenosynovitis (tendon-friction rubs /TFRs/) is a frequent finding in SSc. Patients with TFR are at increased risk of developing renal, vascular, cardiac and gastrointestinal involvement and have reduced survival rates. Changes of fibrinous tenosynovitis can be objectively detected by ultrasound and may be used as an outcome measure in the treatment of MSK involvement." @default.
• W2570662880 created "2017-01-13" @default.
• W2570662880 creator A5002860563 @default.
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• W2570662880 creator A5039081887 @default.
• W2570662880 creator A5064557440 @default.
• W2570662880 date "2016-12-28" @default.
• W2570662880 modified "2023-10-12" @default.
• W2570662880 title "Musculoskeletal Involvement in Systemic Sclerosis: An Unexplored Aspect of the Disease" @default.
• W2570662880 cites W1538849949 @default.
• W2570662880 cites W1541316315 @default.
• W2570662880 cites W1550002364 @default.
• W2570662880 cites W1576420303 @default.
• W2570662880 cites W1588610010 @default.
• W2570662880 cites W1602151893 @default.
• W2570662880 cites W1730836922 @default.
• W2570662880 cites W1943973792 @default.
• W2570662880 cites W1950242095 @default.
• W2570662880 cites W1964373595 @default.
• W2570662880 cites W1965468280 @default.
• W2570662880 cites W1969406005 @default.
• W2570662880 cites W1969642974 @default.
• W2570662880 cites W1969868683 @default.
• W2570662880 cites W1972725992 @default.
• W2570662880 cites W1973843470 @default.
• W2570662880 cites W1977926705 @default.
• W2570662880 cites W1979732714 @default.
• W2570662880 cites W1979917224 @default.
• W2570662880 cites W1983426248 @default.
• W2570662880 cites W1985150349 @default.
• W2570662880 cites W1987821434 @default.
• W2570662880 cites W1990928108 @default.
• W2570662880 cites W1992760786 @default.
• W2570662880 cites W1993296447 @default.
• W2570662880 cites W1993820054 @default.
• W2570662880 cites W1996328355 @default.
• W2570662880 cites W1996842986 @default.
• W2570662880 cites W1997474214 @default.
• W2570662880 cites W1998916323 @default.
• W2570662880 cites W2001739757 @default.
• W2570662880 cites W2008442280 @default.
• W2570662880 cites W2009531778 @default.
• W2570662880 cites W2010217086 @default.
• W2570662880 cites W2010426653 @default.
• W2570662880 cites W2011870315 @default.
• W2570662880 cites W2012867589 @default.
• W2570662880 cites W2017164646 @default.
• W2570662880 cites W2017472623 @default.
• W2570662880 cites W2020138503 @default.
• W2570662880 cites W2022171526 @default.
• W2570662880 cites W2025941853 @default.
• W2570662880 cites W2027761902 @default.
• W2570662880 cites W2032285400 @default.
• W2570662880 cites W2032839364 @default.
• W2570662880 cites W2035210646 @default.
• W2570662880 cites W2036170479 @default.
• W2570662880 cites W2040235061 @default.
• W2570662880 cites W2041467216 @default.
• W2570662880 cites W2045208489 @default.
• W2570662880 cites W2053721836 @default.
• W2570662880 cites W2055640191 @default.
• W2570662880 cites W2058274334 @default.
• W2570662880 cites W2061115469 @default.
• W2570662880 cites W2065930969 @default.
• W2570662880 cites W2066293475 @default.
• W2570662880 cites W2066307481 @default.
• W2570662880 cites W2067868870 @default.
• W2570662880 cites W2069405250 @default.
• W2570662880 cites W2069822756 @default.
• W2570662880 cites W2070575912 @default.
• W2570662880 cites W2071647420 @default.
• W2570662880 cites W2076545156 @default.
• W2570662880 cites W2077193899 @default.
• W2570662880 cites W2078022252 @default.
• W2570662880 cites W2079754986 @default.
• W2570662880 cites W2083141507 @default.
• W2570662880 cites W2086269921 @default.
• W2570662880 cites W2088846949 @default.
• W2570662880 cites W2088878861 @default.
• W2570662880 cites W2090712463 @default.
• W2570662880 cites W2090841051 @default.
• W2570662880 cites W2093799426 @default.
• W2570662880 cites W2095532898 @default.
• W2570662880 cites W2097698354 @default.
• W2570662880 cites W2098125791 @default.
• W2570662880 cites W2098147369 @default.
• W2570662880 cites W2098471340 @default.
• W2570662880 cites W2098713673 @default.
• W2570662880 cites W2101971767 @default.
• W2570662880 cites W2103484137 @default.
• W2570662880 cites W2105316222 @default.
• W2570662880 cites W2106169845 @default.
• W2570662880 cites W2107099748 @default.
• W2570662880 cites W2110604741 @default.
• W2570662880 cites W2113162173 @default.
• W2570662880 cites W2115779116 @default.

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