Matches in SemOpenAlex for { <https://semopenalex.org/work/W2570796584> ?p ?o ?g. }
- W2570796584 endingPage "e0169172" @default.
- W2570796584 startingPage "e0169172" @default.
- W2570796584 abstract "Radiomics aims to quantitatively capture the complex tumor phenotype contained in medical images to associate them with clinical outcomes. This study investigates the impact of different types of computed tomography (CT) images on the prognostic performance of radiomic features for disease recurrence in early stage non-small cell lung cancer (NSCLC) patients treated with stereotactic body radiation therapy (SBRT). 112 early stage NSCLC patients treated with SBRT that had static free breathing (FB) and average intensity projection (AIP) images were analyzed. Nineteen radiomic features were selected from each image type (FB or AIP) for analysis based on stability and variance. The selected FB and AIP radiomic feature sets had 6 common radiomic features between both image types and 13 unique features. The prognostic performances of the features for distant metastasis (DM) and locoregional recurrence (LRR) were evaluated using the concordance index (CI) and compared with two conventional features (tumor volume and maximum diameter). P-values were corrected for multiple testing using the false discovery rate procedure. None of the FB radiomic features were associated with DM, however, seven AIP radiomic features, that described tumor shape and heterogeneity, were (CI range: 0.638–0.676). Conventional features from FB images were not associated with DM, however, AIP conventional features were (CI range: 0.643–0.658). Radiomic and conventional multivariate models were compared between FB and AIP images using cross validation. The differences between the models were assessed using a permutation test. AIP radiomic multivariate models (median CI = 0.667) outperformed all other models (median CI range: 0.601–0.630) in predicting DM. None of the imaging features were prognostic of LRR. Therefore, image type impacts the performance of radiomic models in their association with disease recurrence. AIP images contained more information than FB images that were associated with disease recurrence in early stage NSCLC patients treated with SBRT, which suggests that AIP images may potentially be more optimal for the development of an imaging biomarker." @default.
- W2570796584 created "2017-01-13" @default.
- W2570796584 creator A5001452511 @default.
- W2570796584 creator A5025745523 @default.
- W2570796584 creator A5035783191 @default.
- W2570796584 creator A5040597427 @default.
- W2570796584 creator A5049138051 @default.
- W2570796584 creator A5056992469 @default.
- W2570796584 creator A5064724289 @default.
- W2570796584 creator A5069777488 @default.
- W2570796584 creator A5073247985 @default.
- W2570796584 creator A5079419356 @default.
- W2570796584 date "2017-01-03" @default.
- W2570796584 modified "2023-10-16" @default.
- W2570796584 title "Associations of Radiomic Data Extracted from Static and Respiratory-Gated CT Scans with Disease Recurrence in Lung Cancer Patients Treated with SBRT" @default.
- W2570796584 cites W1969604869 @default.
- W2570796584 cites W1981905971 @default.
- W2570796584 cites W1987054640 @default.
- W2570796584 cites W2010715845 @default.
- W2570796584 cites W2041140147 @default.
- W2570796584 cites W2051021899 @default.
- W2570796584 cites W2053356695 @default.
- W2570796584 cites W2054974480 @default.
- W2570796584 cites W2055575746 @default.
- W2570796584 cites W2060998828 @default.
- W2570796584 cites W2063247340 @default.
- W2570796584 cites W2087676836 @default.
- W2570796584 cites W2097475056 @default.
- W2570796584 cites W2103004421 @default.
- W2570796584 cites W2106893486 @default.
- W2570796584 cites W2112097252 @default.
- W2570796584 cites W2115646671 @default.
- W2570796584 cites W2119805434 @default.
- W2570796584 cites W2119872305 @default.
- W2570796584 cites W2120919324 @default.
- W2570796584 cites W2121203541 @default.
- W2570796584 cites W2124932867 @default.
- W2570796584 cites W2128360321 @default.
- W2570796584 cites W2128625986 @default.
- W2570796584 cites W2128739912 @default.
- W2570796584 cites W2129925362 @default.
- W2570796584 cites W2151480498 @default.
- W2570796584 cites W2229927814 @default.
- W2570796584 cites W2231056033 @default.
- W2570796584 cites W2253150690 @default.
- W2570796584 cites W2290799690 @default.
- W2570796584 cites W2327203407 @default.
- W2570796584 cites W2346343836 @default.
- W2570796584 cites W2398056625 @default.
- W2570796584 cites W402335930 @default.
- W2570796584 cites W4239721925 @default.
- W2570796584 doi "https://doi.org/10.1371/journal.pone.0169172" @default.
- W2570796584 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5207741" @default.
- W2570796584 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28046060" @default.
- W2570796584 hasPublicationYear "2017" @default.
- W2570796584 type Work @default.
- W2570796584 sameAs 2570796584 @default.
- W2570796584 citedByCount "82" @default.
- W2570796584 countsByYear W25707965842017 @default.
- W2570796584 countsByYear W25707965842018 @default.
- W2570796584 countsByYear W25707965842019 @default.
- W2570796584 countsByYear W25707965842020 @default.
- W2570796584 countsByYear W25707965842021 @default.
- W2570796584 countsByYear W25707965842022 @default.
- W2570796584 countsByYear W25707965842023 @default.
- W2570796584 crossrefType "journal-article" @default.
- W2570796584 hasAuthorship W2570796584A5001452511 @default.
- W2570796584 hasAuthorship W2570796584A5025745523 @default.
- W2570796584 hasAuthorship W2570796584A5035783191 @default.
- W2570796584 hasAuthorship W2570796584A5040597427 @default.
- W2570796584 hasAuthorship W2570796584A5049138051 @default.
- W2570796584 hasAuthorship W2570796584A5056992469 @default.
- W2570796584 hasAuthorship W2570796584A5064724289 @default.
- W2570796584 hasAuthorship W2570796584A5069777488 @default.
- W2570796584 hasAuthorship W2570796584A5073247985 @default.
- W2570796584 hasAuthorship W2570796584A5079419356 @default.
- W2570796584 hasBestOaLocation W25707965841 @default.
- W2570796584 hasConcept C126322002 @default.
- W2570796584 hasConcept C126838900 @default.
- W2570796584 hasConcept C142724271 @default.
- W2570796584 hasConcept C2776178081 @default.
- W2570796584 hasConcept C2776256026 @default.
- W2570796584 hasConcept C2777714996 @default.
- W2570796584 hasConcept C2778559731 @default.
- W2570796584 hasConcept C2779134260 @default.
- W2570796584 hasConcept C2989005 @default.
- W2570796584 hasConcept C534529494 @default.
- W2570796584 hasConcept C544519230 @default.
- W2570796584 hasConcept C71924100 @default.
- W2570796584 hasConceptScore W2570796584C126322002 @default.
- W2570796584 hasConceptScore W2570796584C126838900 @default.
- W2570796584 hasConceptScore W2570796584C142724271 @default.
- W2570796584 hasConceptScore W2570796584C2776178081 @default.
- W2570796584 hasConceptScore W2570796584C2776256026 @default.
- W2570796584 hasConceptScore W2570796584C2777714996 @default.
- W2570796584 hasConceptScore W2570796584C2778559731 @default.
- W2570796584 hasConceptScore W2570796584C2779134260 @default.
- W2570796584 hasConceptScore W2570796584C2989005 @default.