FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2570797908> ?p ?o ?g. }

• W2570797908 endingPage "77" @default.
• W2570797908 startingPage "73" @default.
• W2570797908 abstract "Aims Vancomycin is commonly added to acrylic bone cement during revision arthroplasty surgery. Proprietary cement preparations containing vancomycin are available, but are significantly more expensive. We investigated whether the elution of antibiotic from ‘home-made’ cement containing vancomycin was comparable with more expensive commercially available vancomycin impregnated cement. Materials and Methods A total of 18 cement discs containing either proprietary CopalG+V; or ‘home-made’ CopalR+G with vancomycin added by hand, were made. Each disc contained the same amount of antibiotic (0.5 g gentamycin, 2 g vancomycin) and was immersed in ammonium acetate buffer in a sealed container. Fluid from each container was sampled at eight time points over a two-week period. The concentrations of gentamicin and vancomycin in the fluid were analysed using high performance liquid chromatography mass spectrometry. Results The highest peak concentrations of antibiotic were observed from the ‘home-made’ cements containing vancomycin, added as in the operating theatre. The overall elution of antibiotic was, fivefold (vancomycin) and twofold (gentamicin) greater from the ‘home-made’ mix compared with the commercially mixed cement. The use of a vacuum during mixing had no significant effect on antibiotic elution in any of the samples. Conclusion These findings suggest that the addition of 2 g vancomycin powder to gentamicin-impregnated bone cement by hand significantly increases the elution of both antibiotics compared with commercially prepared cements containing vancomycin. We found no significant advantages of using expensive commercially produced vancomycin-impregnated cement and recommend the addition of vancomycin powder by hand in the operating theatre. Cite this article: Bone Joint J 2017;99-B:73–7." @default.
• W2570797908 created "2017-01-13" @default.
• W2570797908 creator A5016789226 @default.
• W2570797908 creator A5023354913 @default.
• W2570797908 creator A5034426792 @default.
• W2570797908 creator A5067660274 @default.
• W2570797908 creator A5083181568 @default.
• W2570797908 date "2017-01-01" @default.
• W2570797908 modified "2023-10-01" @default.
• W2570797908 title "Comparison of the elution properties of commercially available gentamicin and bone cement containing vancomycin with ‘home-made’ preparations" @default.
• W2570797908 cites W1985771574 @default.
• W2570797908 cites W1988290011 @default.
• W2570797908 cites W1997998296 @default.
• W2570797908 cites W2007511756 @default.
• W2570797908 cites W2023825271 @default.
• W2570797908 cites W2030867698 @default.
• W2570797908 cites W2040058520 @default.
• W2570797908 cites W2051787900 @default.
• W2570797908 cites W2054292334 @default.
• W2570797908 cites W2054468082 @default.
• W2570797908 cites W2072902945 @default.
• W2570797908 cites W2091080046 @default.
• W2570797908 cites W2095617904 @default.
• W2570797908 cites W2098151685 @default.
• W2570797908 cites W2100259411 @default.
• W2570797908 cites W2109872165 @default.
• W2570797908 cites W2132505663 @default.
• W2570797908 cites W2133797445 @default.
• W2570797908 cites W2138202752 @default.
• W2570797908 cites W2150525723 @default.
• W2570797908 cites W2152965534 @default.
• W2570797908 cites W2160564583 @default.
• W2570797908 cites W2165756051 @default.
• W2570797908 cites W2168695568 @default.
• W2570797908 cites W2182376589 @default.
• W2570797908 cites W2189248853 @default.
• W2570797908 cites W2233872637 @default.
• W2570797908 cites W2267092934 @default.
• W2570797908 cites W2324240896 @default.
• W2570797908 cites W2329001363 @default.
• W2570797908 cites W4213354399 @default.
• W2570797908 cites W4248009303 @default.
• W2570797908 doi "https://doi.org/10.1302/0301-620x.99b1.bjj-2016-0566.r1" @default.
• W2570797908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28053260" @default.
• W2570797908 hasPublicationYear "2017" @default.
• W2570797908 type Work @default.
• W2570797908 sameAs 2570797908 @default.
• W2570797908 citedByCount "49" @default.
• W2570797908 countsByYear W25707979082017 @default.
• W2570797908 countsByYear W25707979082018 @default.
• W2570797908 countsByYear W25707979082019 @default.
• W2570797908 countsByYear W25707979082020 @default.
• W2570797908 countsByYear W25707979082021 @default.
• W2570797908 countsByYear W25707979082022 @default.
• W2570797908 countsByYear W25707979082023 @default.
• W2570797908 crossrefType "journal-article" @default.
• W2570797908 hasAuthorship W2570797908A5016789226 @default.
• W2570797908 hasAuthorship W2570797908A5023354913 @default.
• W2570797908 hasAuthorship W2570797908A5034426792 @default.
• W2570797908 hasAuthorship W2570797908A5067660274 @default.
• W2570797908 hasAuthorship W2570797908A5083181568 @default.
• W2570797908 hasConcept C159985019 @default.
• W2570797908 hasConcept C185592680 @default.
• W2570797908 hasConcept C192562407 @default.
• W2570797908 hasConcept C2775832221 @default.
• W2570797908 hasConcept C2778891590 @default.
• W2570797908 hasConcept C2778980435 @default.
• W2570797908 hasConcept C2779489039 @default.
• W2570797908 hasConcept C43617362 @default.
• W2570797908 hasConcept C501593827 @default.
• W2570797908 hasConcept C523546767 @default.
• W2570797908 hasConcept C523993062 @default.
• W2570797908 hasConcept C54355233 @default.
• W2570797908 hasConcept C55493867 @default.
• W2570797908 hasConcept C71924100 @default.
• W2570797908 hasConcept C73826308 @default.
• W2570797908 hasConcept C86803240 @default.
• W2570797908 hasConceptScore W2570797908C159985019 @default.
• W2570797908 hasConceptScore W2570797908C185592680 @default.
• W2570797908 hasConceptScore W2570797908C192562407 @default.
• W2570797908 hasConceptScore W2570797908C2775832221 @default.
• W2570797908 hasConceptScore W2570797908C2778891590 @default.
• W2570797908 hasConceptScore W2570797908C2778980435 @default.
• W2570797908 hasConceptScore W2570797908C2779489039 @default.
• W2570797908 hasConceptScore W2570797908C43617362 @default.
• W2570797908 hasConceptScore W2570797908C501593827 @default.
• W2570797908 hasConceptScore W2570797908C523546767 @default.
• W2570797908 hasConceptScore W2570797908C523993062 @default.
• W2570797908 hasConceptScore W2570797908C54355233 @default.
• W2570797908 hasConceptScore W2570797908C55493867 @default.
• W2570797908 hasConceptScore W2570797908C71924100 @default.
• W2570797908 hasConceptScore W2570797908C73826308 @default.
• W2570797908 hasConceptScore W2570797908C86803240 @default.
• W2570797908 hasIssue "1" @default.
• W2570797908 hasLocation W25707979081 @default.
• W2570797908 hasLocation W25707979082 @default.
• W2570797908 hasOpenAccess W2570797908 @default.
• W2570797908 hasPrimaryLocation W25707979081 @default.

• next