FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2571319199> ?p ?o ?g. }

• W2571319199 endingPage "e0168856" @default.
• W2571319199 startingPage "e0168856" @default.
• W2571319199 abstract "Cancer cells and stromal cells cooperate by exchanging diffusible factors that sustain tumor growth, a form of frequency-dependent selection that can be studied in the framework of evolutionary game theory. In the case of multiple myeloma, three types of cells (malignant plasma cells, osteoblasts and osteoclasts) exchange growth factors with different effects, and tumor-stroma interactions have been analysed using a model of cooperation with pairwise interactions. Here we show that a model in which growth factors have autocrine and paracrine effects on multiple cells, a more realistic assumption for tumor-stroma interactions, leads to different results, with implications for disease progression and treatment. In particular, the model reveals that reducing the number of malignant plasma cells below a critical threshold can lead to their extinction and thus to restore a healthy balance between osteoclast and osteoblast, a result in line with current therapies against multiple myeloma." @default.
• W2571319199 created "2017-01-13" @default.
• W2571319199 creator A5005001958 @default.
• W2571319199 creator A5019446590 @default.
• W2571319199 creator A5034153477 @default.
• W2571319199 creator A5064114366 @default.
• W2571319199 date "2016-12-28" @default.
• W2571319199 modified "2023-09-24" @default.
• W2571319199 title "Evolutionary Dynamics of Tumor-Stroma Interactions in Multiple Myeloma" @default.
• W2571319199 cites W1965607649 @default.
• W2571319199 cites W1978239979 @default.
• W2571319199 cites W1982972117 @default.
• W2571319199 cites W1985919561 @default.
• W2571319199 cites W2009888511 @default.
• W2571319199 cites W2010727640 @default.
• W2571319199 cites W2011764148 @default.
• W2571319199 cites W2022488821 @default.
• W2571319199 cites W2025969634 @default.
• W2571319199 cites W2034269086 @default.
• W2571319199 cites W2043119216 @default.
• W2571319199 cites W2043500890 @default.
• W2571319199 cites W2064768888 @default.
• W2571319199 cites W2069849016 @default.
• W2571319199 cites W2078400068 @default.
• W2571319199 cites W2089956125 @default.
• W2571319199 cites W2095098163 @default.
• W2571319199 cites W2095412173 @default.
• W2571319199 cites W2107844041 @default.
• W2571319199 cites W2122038117 @default.
• W2571319199 cites W2122860450 @default.
• W2571319199 cites W2124411815 @default.
• W2571319199 cites W2127771118 @default.
• W2571319199 cites W2152091753 @default.
• W2571319199 cites W2166182174 @default.
• W2571319199 cites W2169183166 @default.
• W2571319199 cites W2609515889 @default.
• W2571319199 cites W3098439297 @default.
• W2571319199 cites W4238509480 @default.
• W2571319199 doi "https://doi.org/10.1371/journal.pone.0168856" @default.
• W2571319199 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5193458" @default.
• W2571319199 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28030607" @default.
• W2571319199 hasPublicationYear "2016" @default.
• W2571319199 type Work @default.
• W2571319199 sameAs 2571319199 @default.
• W2571319199 citedByCount "10" @default.
• W2571319199 countsByYear W25713191992017 @default.
• W2571319199 countsByYear W25713191992018 @default.
• W2571319199 countsByYear W25713191992020 @default.
• W2571319199 countsByYear W25713191992021 @default.
• W2571319199 countsByYear W25713191992022 @default.
• W2571319199 crossrefType "journal-article" @default.
• W2571319199 hasAuthorship W2571319199A5005001958 @default.
• W2571319199 hasAuthorship W2571319199A5019446590 @default.
• W2571319199 hasAuthorship W2571319199A5034153477 @default.
• W2571319199 hasAuthorship W2571319199A5064114366 @default.
• W2571319199 hasBestOaLocation W25713191991 @default.
• W2571319199 hasConcept C121608353 @default.
• W2571319199 hasConcept C128240485 @default.
• W2571319199 hasConcept C16930146 @default.
• W2571319199 hasConcept C170493617 @default.
• W2571319199 hasConcept C202751555 @default.
• W2571319199 hasConcept C203014093 @default.
• W2571319199 hasConcept C204232928 @default.
• W2571319199 hasConcept C2776033226 @default.
• W2571319199 hasConcept C2776107976 @default.
• W2571319199 hasConcept C2776364478 @default.
• W2571319199 hasConcept C2778260815 @default.
• W2571319199 hasConcept C3020616263 @default.
• W2571319199 hasConcept C502942594 @default.
• W2571319199 hasConcept C52124034 @default.
• W2571319199 hasConcept C54355233 @default.
• W2571319199 hasConcept C7876069 @default.
• W2571319199 hasConcept C81885089 @default.
• W2571319199 hasConcept C86803240 @default.
• W2571319199 hasConcept C95444343 @default.
• W2571319199 hasConcept C96232424 @default.
• W2571319199 hasConceptScore W2571319199C121608353 @default.
• W2571319199 hasConceptScore W2571319199C128240485 @default.
• W2571319199 hasConceptScore W2571319199C16930146 @default.
• W2571319199 hasConceptScore W2571319199C170493617 @default.
• W2571319199 hasConceptScore W2571319199C202751555 @default.
• W2571319199 hasConceptScore W2571319199C203014093 @default.
• W2571319199 hasConceptScore W2571319199C204232928 @default.
• W2571319199 hasConceptScore W2571319199C2776033226 @default.
• W2571319199 hasConceptScore W2571319199C2776107976 @default.
• W2571319199 hasConceptScore W2571319199C2776364478 @default.
• W2571319199 hasConceptScore W2571319199C2778260815 @default.
• W2571319199 hasConceptScore W2571319199C3020616263 @default.
• W2571319199 hasConceptScore W2571319199C502942594 @default.
• W2571319199 hasConceptScore W2571319199C52124034 @default.
• W2571319199 hasConceptScore W2571319199C54355233 @default.
• W2571319199 hasConceptScore W2571319199C7876069 @default.
• W2571319199 hasConceptScore W2571319199C81885089 @default.
• W2571319199 hasConceptScore W2571319199C86803240 @default.
• W2571319199 hasConceptScore W2571319199C95444343 @default.
• W2571319199 hasConceptScore W2571319199C96232424 @default.
• W2571319199 hasIssue "12" @default.
• W2571319199 hasLocation W25713191991 @default.

• next