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- W2572202623 abstract "The present investigations were undertaken to study the effect of in vivo administration of FK565 on the process of hemopoiesis in normal and tumor-bearing mice. FK565 administration (10 mg/kg body weight) of normal mice resulted in an enhancement of the bone marrow cell (BMC) colony foming activity (CFA) and proliferation in vitro. The counts of granulocyte- and granulocyte macrophage-colony forming units (CFU-G and CFU-GM) were significantly enhanced in the BMC of FK565-treated group. The total leukocyte count (TLC) was also augmented after FK565 administration. The differential leukocyte count (DLC) revealed an enhancement of the neutrophil count in the FK565-treated mice. A similar pattern of BMC proliferation, CFA, TLC and DLC was observed in P815 tumor-bearing mice. FK565 administration of the tumor-bearing mice, however, did not significantly alter the CFA, TLC and DLC." @default.
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- W2572202623 date "1995-05-01" @default.
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- W2572202623 title "Modulation of Hemopoiesis in Normal and Tumor-Bearing Mice on<i>in Vivo</i>Administration of FK565" @default.
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- W2572202623 doi "https://doi.org/10.1177/039463209500800205" @default.
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