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- W2573023629 abstract "Abstract Studies of Xenopus eye development have contributed considerably to the understanding of vertebrate neurogenesis, including eye field specification, cell fate determination and identification of genes critical for eye formation. This knowledge has served as a solid foundation for cellular and molecular examinations of the robust regenerative capacity of the Xenopus eye. The retina, lens, and the optic nerve are capable of regeneration after injury in both larval and adult stages. Here, we discuss the current models for studying eye regeneration in Xenopus and their potential applications for providing insights into human eye diseases. As Xenopus has many of the same tools that are available for other regeneration models, we thus highlight the distinct strengths and versatility of this organism that make it especially suited for extrapolating and testing strategies aimed at promoting regeneration and repair in eye tissues. Furthermore, we outline a promising future for the use of new techniques and approaches to address outstanding questions in understanding eye regeneration." @default.
- W2573023629 created "2017-01-26" @default.
- W2573023629 creator A5031098170 @default.
- W2573023629 date "2017-01-01" @default.
- W2573023629 modified "2023-10-03" @default.
- W2573023629 title "Seeing the future: usingXenopusto understand eye regeneration" @default.
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- W2573023629 doi "https://doi.org/10.1002/dvg.23003" @default.
- W2573023629 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28095643" @default.
- W2573023629 hasPublicationYear "2017" @default.
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