FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2573436930> ?p ?o ?g. }

• W2573436930 abstract "Ovarian transplantation is a useful method for preserving the fertility of young women with cancer who undergo radiotherapy and chemotherapy. Follicle-stimulating hormone (FSH) is use to protect transplanted ovarian tissues from ischemia injury through promoting revascularization after transplantation, but the side effect of high level FSH is ovarian overstimulation leading to substantial follicular loss. In this study, we investigated the optimal usage of FSH on revascularization in the in vitro cultured ovarian tissues before and after transplantation. FSH mainly exhibited an additive response in the gene and protein expression of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF) and follicle stimulating hormone receptor (FSHR) with its raised concentrations (0.15 IU/ml, 0.30 IU/ml and 0.60 IU/ml) and prolonged treatment (3 h, 6 h, 12 h, 24 h). The concentrations with 0.60 IU/ml FSH could obviously promoted the expression of VEGF, bFGF and FSHR, but under this concentration FSH could also overstimulated the ovarian tissue leading to follicular loss. With the increase of culture time, the gene and protein expression of VEGF and bFGF both were up-regulated in all of the FSH added groups, but FSHR expression decreased when culture time exceeded 12 h. So we chose 0.30 IU/ml FSH added concentration and 6 h culture time as the FSH usage condition in functional revascularization verification experiment, and found that under this condition FSH promoted 2.5 times increase of vascular density in treated group than in control group after ovarian tissues transplantation. Ovarian intervention with 0.30 IU/ml FSH for 6 h is an optimal FSH usage condition which could accelerate the revascularization in the allotransplanted ovarian tissue and can not produce ovarian overstimulation." @default.
• W2573436930 created "2017-01-26" @default.
• W2573436930 creator A5006535608 @default.
• W2573436930 creator A5015452019 @default.
• W2573436930 creator A5045162177 @default.
• W2573436930 creator A5047699684 @default.
• W2573436930 creator A5047808650 @default.
• W2573436930 creator A5050645272 @default.
• W2573436930 creator A5053119562 @default.
• W2573436930 creator A5062200668 @default.
• W2573436930 creator A5065251363 @default.
• W2573436930 creator A5066466989 @default.
• W2573436930 date "2017-01-17" @default.
• W2573436930 modified "2023-10-18" @default.
• W2573436930 title "Optimal FSH usage in revascularization of allotransplanted ovarian tissue in mice" @default.
• W2573436930 cites W1521176860 @default.
• W2573436930 cites W1889600125 @default.
• W2573436930 cites W195660633 @default.
• W2573436930 cites W1968907465 @default.
• W2573436930 cites W1969435540 @default.
• W2573436930 cites W1969704093 @default.
• W2573436930 cites W1975137245 @default.
• W2573436930 cites W1976162913 @default.
• W2573436930 cites W1976729353 @default.
• W2573436930 cites W1982837090 @default.
• W2573436930 cites W2003261621 @default.
• W2573436930 cites W2003539719 @default.
• W2573436930 cites W2005250335 @default.
• W2573436930 cites W2015054574 @default.
• W2573436930 cites W2017732958 @default.
• W2573436930 cites W2019372248 @default.
• W2573436930 cites W2028824685 @default.
• W2573436930 cites W2029193079 @default.
• W2573436930 cites W2049630436 @default.
• W2573436930 cites W2052334717 @default.
• W2573436930 cites W2060744395 @default.
• W2573436930 cites W2063965256 @default.
• W2573436930 cites W2075698995 @default.
• W2573436930 cites W2076184598 @default.
• W2573436930 cites W2110883787 @default.
• W2573436930 cites W2111054018 @default.
• W2573436930 cites W2118782553 @default.
• W2573436930 cites W2132086132 @default.
• W2573436930 cites W2133041809 @default.
• W2573436930 cites W2133357482 @default.
• W2573436930 cites W2143157162 @default.
• W2573436930 cites W2150663786 @default.
• W2573436930 cites W2153820217 @default.
• W2573436930 cites W2162137928 @default.
• W2573436930 cites W2169525543 @default.
• W2573436930 cites W2171771184 @default.
• W2573436930 cites W2183374905 @default.
• W2573436930 cites W2412328276 @default.
• W2573436930 doi "https://doi.org/10.1186/s13048-016-0299-7" @default.
• W2573436930 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5240196" @default.
• W2573436930 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28095884" @default.
• W2573436930 hasPublicationYear "2017" @default.
• W2573436930 type Work @default.
• W2573436930 sameAs 2573436930 @default.
• W2573436930 citedByCount "7" @default.
• W2573436930 countsByYear W25734369302020 @default.
• W2573436930 countsByYear W25734369302021 @default.
• W2573436930 countsByYear W25734369302022 @default.
• W2573436930 countsByYear W25734369302023 @default.
• W2573436930 crossrefType "journal-article" @default.
• W2573436930 hasAuthorship W2573436930A5006535608 @default.
• W2573436930 hasAuthorship W2573436930A5015452019 @default.
• W2573436930 hasAuthorship W2573436930A5045162177 @default.
• W2573436930 hasAuthorship W2573436930A5047699684 @default.
• W2573436930 hasAuthorship W2573436930A5047808650 @default.
• W2573436930 hasAuthorship W2573436930A5050645272 @default.
• W2573436930 hasAuthorship W2573436930A5053119562 @default.
• W2573436930 hasAuthorship W2573436930A5062200668 @default.
• W2573436930 hasAuthorship W2573436930A5065251363 @default.
• W2573436930 hasAuthorship W2573436930A5066466989 @default.
• W2573436930 hasBestOaLocation W25734369301 @default.
• W2573436930 hasConcept C102570824 @default.
• W2573436930 hasConcept C126322002 @default.
• W2573436930 hasConcept C134018914 @default.
• W2573436930 hasConcept C16685009 @default.
• W2573436930 hasConcept C167734588 @default.
• W2573436930 hasConcept C170493617 @default.
• W2573436930 hasConcept C179933525 @default.
• W2573436930 hasConcept C18597862 @default.
• W2573436930 hasConcept C187785154 @default.
• W2573436930 hasConcept C196843134 @default.
• W2573436930 hasConcept C2775960820 @default.
• W2573436930 hasConcept C2776600139 @default.
• W2573436930 hasConcept C2777025900 @default.
• W2573436930 hasConcept C2777587049 @default.
• W2573436930 hasConcept C2777688143 @default.
• W2573436930 hasConcept C2777904497 @default.
• W2573436930 hasConcept C2778324911 @default.
• W2573436930 hasConcept C2778575703 @default.
• W2573436930 hasConcept C2779234561 @default.
• W2573436930 hasConcept C2779279165 @default.
• W2573436930 hasConcept C2780536345 @default.
• W2573436930 hasConcept C2908647359 @default.
• W2573436930 hasConcept C2911091166 @default.
• W2573436930 hasConcept C29390026 @default.

• next