FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2574091036> ?p ?o ?g. }

• W2574091036 endingPage "35" @default.
• W2574091036 startingPage "24" @default.
• W2574091036 abstract "Ghrelin and nesfatin-1 are two peptidyl hormones primarily involved in food intake regulation. We previously reported that the amount of dietary carbohydrates, protein and lipids modulates the expression of these peptides in goldfish in vivo. In the present work, we aimed to characterize the effects of single nutrients on ghrelin and nesfatin-1 in the intestine and hepatopancreas. First, immunolocalization of ghrelin and NUCB2/nesfatin-1 in goldfish hepatopancreas cells was studied by immunohistochemistry. Second, the effects of 2 and 4 hour-long exposures of cultured intestine and hepatopancreas sections to glucose, l-tryptophan, oleic acid, linolenic acid (LNA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on ghrelin and nesfatin-1 gene and protein expression were studied. Co-localization of ghrelin and NUCB2/nesfatin-1 in the cytoplasm of goldfish hepatocytes was found. Exposure to glucose led to an upregulation of preproghrelin and a downregulation of nucb2/nesfatin-1 in the intestine. l-Tryptophan mainly decreased the expression of both peptides in the intestine and hepatopancreas. Fatty acids, in general, downregulated NUCB2/nesfatin-1 in the intestine, but only the longer and highly unsaturated fatty acids inhibited preproghrelin. EPA exposure led to a decrease in preproghrelin, and an increase in nucb2/nesfatin-1 expression in hepatopancreas after 2 h. These results show that macronutrients exert a dose- and time-dependent, direct regulation of ghrelin and nesfatin-1 in the intestine and hepatopancreas, and suggest a role for these hormones in the digestive process and nutrient metabolism." @default.
• W2574091036 created "2017-01-26" @default.
• W2574091036 creator A5019585960 @default.
• W2574091036 creator A5039998343 @default.
• W2574091036 creator A5061814946 @default.
• W2574091036 creator A5078993982 @default.
• W2574091036 date "2017-04-01" @default.
• W2574091036 modified "2023-09-30" @default.
• W2574091036 title "Glucose, amino acids and fatty acids directly regulate ghrelin and NUCB2/nesfatin-1 in the intestine and hepatopancreas of goldfish (Carassius auratus) in vitro" @default.
• W2574091036 cites W1494332264 @default.
• W2574091036 cites W1499872721 @default.
• W2574091036 cites W1533185304 @default.
• W2574091036 cites W1578951740 @default.
• W2574091036 cites W1599926903 @default.
• W2574091036 cites W1619946532 @default.
• W2574091036 cites W1637971961 @default.
• W2574091036 cites W1966108268 @default.
• W2574091036 cites W1969709159 @default.
• W2574091036 cites W1970089300 @default.
• W2574091036 cites W1973261847 @default.
• W2574091036 cites W1975554506 @default.
• W2574091036 cites W1987092293 @default.
• W2574091036 cites W1987687515 @default.
• W2574091036 cites W1988061519 @default.
• W2574091036 cites W1994976886 @default.
• W2574091036 cites W1995123519 @default.
• W2574091036 cites W1995918388 @default.
• W2574091036 cites W2002803975 @default.
• W2574091036 cites W2010204002 @default.
• W2574091036 cites W2017136878 @default.
• W2574091036 cites W2020727714 @default.
• W2574091036 cites W2029228544 @default.
• W2574091036 cites W2031496368 @default.
• W2574091036 cites W2034697008 @default.
• W2574091036 cites W2039644016 @default.
• W2574091036 cites W2044783219 @default.
• W2574091036 cites W2048178217 @default.
• W2574091036 cites W2048194663 @default.
• W2574091036 cites W2048447383 @default.
• W2574091036 cites W2049033436 @default.
• W2574091036 cites W2054036736 @default.
• W2574091036 cites W2055891822 @default.
• W2574091036 cites W2056380561 @default.
• W2574091036 cites W2057465255 @default.
• W2574091036 cites W2057712755 @default.
• W2574091036 cites W2063816197 @default.
• W2574091036 cites W2064081737 @default.
• W2574091036 cites W2065400887 @default.
• W2574091036 cites W2070266571 @default.
• W2574091036 cites W2073628217 @default.
• W2574091036 cites W2075952160 @default.
• W2574091036 cites W2076907128 @default.
• W2574091036 cites W2083210381 @default.
• W2574091036 cites W2083376317 @default.
• W2574091036 cites W2083941130 @default.
• W2574091036 cites W2084904359 @default.
• W2574091036 cites W2087733763 @default.
• W2574091036 cites W2089208707 @default.
• W2574091036 cites W2089656605 @default.
• W2574091036 cites W2095873174 @default.
• W2574091036 cites W2097596167 @default.
• W2574091036 cites W2099115038 @default.
• W2574091036 cites W2107277218 @default.
• W2574091036 cites W2111536564 @default.
• W2574091036 cites W2112202133 @default.
• W2574091036 cites W2116753388 @default.
• W2574091036 cites W2118617555 @default.
• W2574091036 cites W2119264912 @default.
• W2574091036 cites W2137797170 @default.
• W2574091036 cites W2139068363 @default.
• W2574091036 cites W2143647203 @default.
• W2574091036 cites W2144575734 @default.
• W2574091036 cites W2146456530 @default.
• W2574091036 cites W2153175786 @default.
• W2574091036 cites W2163865122 @default.
• W2574091036 cites W2164524654 @default.
• W2574091036 cites W2175432880 @default.
• W2574091036 cites W2280593342 @default.
• W2574091036 cites W2297084813 @default.
• W2574091036 cites W2411371777 @default.
• W2574091036 cites W2563331994 @default.
• W2574091036 cites W826469802 @default.
• W2574091036 doi "https://doi.org/10.1016/j.cbpa.2017.01.006" @default.
• W2574091036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28089858" @default.
• W2574091036 hasPublicationYear "2017" @default.
• W2574091036 type Work @default.
• W2574091036 sameAs 2574091036 @default.
• W2574091036 citedByCount "26" @default.
• W2574091036 countsByYear W25740910362017 @default.
• W2574091036 countsByYear W25740910362018 @default.
• W2574091036 countsByYear W25740910362019 @default.
• W2574091036 countsByYear W25740910362020 @default.
• W2574091036 countsByYear W25740910362021 @default.
• W2574091036 countsByYear W25740910362022 @default.
• W2574091036 countsByYear W25740910362023 @default.
• W2574091036 crossrefType "journal-article" @default.
• W2574091036 hasAuthorship W2574091036A5019585960 @default.
• W2574091036 hasAuthorship W2574091036A5039998343 @default.

• next