Matches in SemOpenAlex for { <https://semopenalex.org/work/W2574503265> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2574503265 endingPage "223" @default.
- W2574503265 startingPage "212" @default.
- W2574503265 abstract "Ets transcription factors are important developmental regulators and have been shown to function as modulators of cell fate. We have previously discovered Ets variant 2 (Etv2) as an essential regulator of the hematoendothelial lineage. We have demonstrated that Etv2 mutant embryos are non-viable and lack hematoendothelial lineages. We have utilized gene editing technologies to define upstream regulators of the Etv2 gene and we and others have defined downstream target genes. Recent studies have demonstrated that Etv2, in combination with co-factors, promote a hematoendothelial fate in differentiating human-induced pluripotent stem cells. Collectively, these studies support the notion that Etv2 is a master regulator of the hematoendothelial lineages. Definition of these master regulators and the use of emerging technologies will provide a platform for engineering large animal models that will be useful for clinical research and regenerative medicine and will potentially impact the treatment of chronic vascular diseases." @default.
- W2574503265 created "2017-01-26" @default.
- W2574503265 creator A5036817888 @default.
- W2574503265 date "2016-01-01" @default.
- W2574503265 modified "2023-09-23" @default.
- W2574503265 title "Etv2 IS A MASTER REGULATOR OF HEMATOENDOTHELIAL LINEAGES." @default.
- W2574503265 cites W1915585572 @default.
- W2574503265 cites W1976235638 @default.
- W2574503265 cites W2007827699 @default.
- W2574503265 cites W2018560113 @default.
- W2574503265 cites W2021868689 @default.
- W2574503265 cites W2029434429 @default.
- W2574503265 cites W2031744447 @default.
- W2574503265 cites W2073675493 @default.
- W2574503265 cites W2079248268 @default.
- W2574503265 cites W2084223203 @default.
- W2574503265 cites W2109418446 @default.
- W2574503265 cites W2110623684 @default.
- W2574503265 cites W2123955451 @default.
- W2574503265 cites W2124231777 @default.
- W2574503265 cites W2157908534 @default.
- W2574503265 cites W2191976225 @default.
- W2574503265 cites W2287778117 @default.
- W2574503265 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5216469" @default.
- W2574503265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28066054" @default.
- W2574503265 hasPublicationYear "2016" @default.
- W2574503265 type Work @default.
- W2574503265 sameAs 2574503265 @default.
- W2574503265 citedByCount "13" @default.
- W2574503265 countsByYear W25745032652017 @default.
- W2574503265 countsByYear W25745032652019 @default.
- W2574503265 countsByYear W25745032652020 @default.
- W2574503265 countsByYear W25745032652021 @default.
- W2574503265 countsByYear W25745032652022 @default.
- W2574503265 crossrefType "journal-article" @default.
- W2574503265 hasAuthorship W2574503265A5036817888 @default.
- W2574503265 hasConcept C104317684 @default.
- W2574503265 hasConcept C107459253 @default.
- W2574503265 hasConcept C145103041 @default.
- W2574503265 hasConcept C150194340 @default.
- W2574503265 hasConcept C163952510 @default.
- W2574503265 hasConcept C165864922 @default.
- W2574503265 hasConcept C2776817793 @default.
- W2574503265 hasConcept C3017607883 @default.
- W2574503265 hasConcept C54355233 @default.
- W2574503265 hasConcept C67339327 @default.
- W2574503265 hasConcept C6929976 @default.
- W2574503265 hasConcept C70721500 @default.
- W2574503265 hasConcept C81350143 @default.
- W2574503265 hasConcept C86339819 @default.
- W2574503265 hasConcept C86803240 @default.
- W2574503265 hasConcept C95444343 @default.
- W2574503265 hasConceptScore W2574503265C104317684 @default.
- W2574503265 hasConceptScore W2574503265C107459253 @default.
- W2574503265 hasConceptScore W2574503265C145103041 @default.
- W2574503265 hasConceptScore W2574503265C150194340 @default.
- W2574503265 hasConceptScore W2574503265C163952510 @default.
- W2574503265 hasConceptScore W2574503265C165864922 @default.
- W2574503265 hasConceptScore W2574503265C2776817793 @default.
- W2574503265 hasConceptScore W2574503265C3017607883 @default.
- W2574503265 hasConceptScore W2574503265C54355233 @default.
- W2574503265 hasConceptScore W2574503265C67339327 @default.
- W2574503265 hasConceptScore W2574503265C6929976 @default.
- W2574503265 hasConceptScore W2574503265C70721500 @default.
- W2574503265 hasConceptScore W2574503265C81350143 @default.
- W2574503265 hasConceptScore W2574503265C86339819 @default.
- W2574503265 hasConceptScore W2574503265C86803240 @default.
- W2574503265 hasConceptScore W2574503265C95444343 @default.
- W2574503265 hasLocation W25745032651 @default.
- W2574503265 hasOpenAccess W2574503265 @default.
- W2574503265 hasPrimaryLocation W25745032651 @default.
- W2574503265 hasRelatedWork W183875134 @default.
- W2574503265 hasRelatedWork W1983690992 @default.
- W2574503265 hasRelatedWork W2002880495 @default.
- W2574503265 hasRelatedWork W2008849368 @default.
- W2574503265 hasRelatedWork W2068674690 @default.
- W2574503265 hasRelatedWork W2167190345 @default.
- W2574503265 hasRelatedWork W2400150343 @default.
- W2574503265 hasRelatedWork W2414895197 @default.
- W2574503265 hasRelatedWork W2574503265 @default.
- W2574503265 hasRelatedWork W2761518775 @default.
- W2574503265 hasVolume "127" @default.
- W2574503265 isParatext "false" @default.
- W2574503265 isRetracted "false" @default.
- W2574503265 magId "2574503265" @default.
- W2574503265 workType "article" @default.