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- W2574742014 abstract "When the standard lepromin was treated with the sonic vibration (9.5 kilocycle per sec.), the corse tissue fragments were dispersed in fine particles, and at the same time the number of leprosy bacilli diminished exponentially. Under the conditions of the experiment, about half of the bacilli was destructed within 5 minutes. The complement-fixing ability of the lepromin with leprous serum was, however, increased by the sonic vibration showing that the active substance was not destroyed by this treatment. Comparison of potency tests on leprosy patients gave the results that the lepromin sonic-vibrated for 30 minutes elicited weaker early reactions than the untreated standard lepromin, while there was no significant difference between them with respect to the late reactions. Consequently, it is considered that the late reaction may be caused not only by the intact leprosy bacilli but also by the mechanically destructed bacilli." @default.
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- W2574742014 date "1963-01-01" @default.
- W2574742014 modified "2023-09-25" @default.
- W2574742014 title "Effect of Sonic Vibration on the Property and Potency of lepromin" @default.
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- W2574742014 doi "https://doi.org/10.5025/hansen1930.32.3_137" @default.
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