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• W2575458506 abstract "Label-free imaging uses inherent contrast mechanisms within cells to create image contrast without introducing dyes/labels, which may confound results. Quantitative phase imaging is label-free and offers higher content and contrast compared to traditional techniques. High-contrast images facilitate generation of individual cell metrics via more robust segmentation and tracking, enabling formation of a label-free dynamic phenotype describing cell-to-cell heterogeneity and temporal changes. Compared to population-level averages, individual cell-level dynamic phenotypes have greater power to differentiate between cellular responses to treatments, which has clinical relevance e.g. in the treatment of cancer. Furthermore, as the data is obtained label-free, the same cells can be used for further assays or expansion, of potential benefit for the fields of regenerative and personalised medicine." @default.
• W2575458506 created "2017-01-26" @default.
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• W2575458506 date "2017-03-01" @default.
• W2575458506 modified "2023-10-12" @default.
• W2575458506 title "Characterising live cell behaviour: Traditional label-free and quantitative phase imaging approaches" @default.
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• W2575458506 doi "https://doi.org/10.1016/j.biocel.2017.01.004" @default.
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