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• W2578954893 abstract "INTRODUCTION: Diagnosis of breast cancer confronts affected women with major challenges. These impaired patients often suffer from aesthetic limitations after tumor removal. Therefore, skin-sparing mastectomy (SSM) or nipple-sparing mastectomy (NSM) offer essential treatment options to achieve a safe-oncological and aesthetic pleasing breast reconstruction. MATERIALS AND METHODS: From 2010 to 2015 in 43 female patients (n = 43), who were diagnosed with breast cancer, 52 skin-sparing mastectomies were performed in our department (28x SSM; 24x NSM). A retrospective data collection with median follow-up time of 3.14 years (range: 1 - 6 years) was carried out. Focus was on tumor entities, tumor recurrence, detection of complications such as seroma/hematoma, infection, capsular contracture, skin perforation and wound healing disorder, kind of breast reconstruction used et cetera. As alternative treatment options only plain mastectomy - going alongside with reduced aesthetic results - can be named. RESULTS: Indications for the performance of a SSM/NSM were tumor biologies, no evidence of cutaneous tumor-infiltration and/or previous history of breast-conserving surgery with R1-resection status. The median patient age was 49 years. Patients suffered from invasive mamma carcinomas (28x; 17x accompanied by DCIS), DCIS (10x), LCIS (1x) or recurrence of breast cancer (3x). Prophylactic NSM/SSM were performed 12 times. Complication rates were statistically analyzed. Local recurrence rate was 9.3% (4/43 pat.) and distant recurrence rate 4.3% (2/43 pat.) with one patient passing away during given follow-up period. There was no increase in tumor recurrence rate after SSM/NSM compared to mastectomy complication rates published in scientific literature. CONCLUSIONS: SSM/NSM is an efficient treatment option for patients suffering from breast cancer. An aesthetic pleasing surgical outcome is a great advantage of this surgical procedure. Our analysis showed a slightly decreased tumor recurrence rate after SSM/NSM compared to rates after just plain mastectomies. But individual treatment requirements should always be taken into account." @default.
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• W2578954893 date "2017-01-01" @default.
• W2578954893 modified "2023-10-16" @default.
• W2578954893 title "Abstract" @default.
• W2578954893 doi "https://doi.org/10.1097/01.gox.0000512400.45663.72" @default.
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