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- W257904097 abstract "This study was conducted on two groups of newborn rats: a control group and anexperimental group. The control group and was composed of seven newborn rats, which were placedat 4 hours after birth, in a pediatric incubator, together with their mother, in conditions of normoxia for21 days. The experimental group consisted of seven newborn rats, which were placed at 4 hours afterbirth, in a pediatric incubator with their mother, in conditions of normoxia for 7 days, then five days ina daily alternating periods of hyperoxia (80%) and hypoxia (10%), and then nine days in conditions ofnormoxia. Slaughtering of the rats was performed on day 21 and the eyeglobes were harvested in orderto perform histopathological examinations. Microscopic examination revealed a normal developmentof the retina in the control group. In the experimental group, on the surface of the retina, anexaggerated neovascularization both respects the number of vessels, as well as their size was observed.Excessive proliferation of blood vessels caused severe histo-architectural changes, irreversible andbilateral, with serious damage of the retinal function." @default.
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- W257904097 date "2010-01-01" @default.
- W257904097 modified "2023-10-17" @default.
- W257904097 title "Retinal Neovascularisation in Newborn Rats Submitted to Variations of Concentrations of Oxygene. Histopatological Aspects" @default.
- W257904097 doi "https://doi.org/10.15835/buasvmcn-vm:67:1:5971" @default.
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