Matches in SemOpenAlex for { <https://semopenalex.org/work/W2579147068> ?p ?o ?g. }
- W2579147068 endingPage "5" @default.
- W2579147068 startingPage "5" @default.
- W2579147068 abstract "microRNAs (miRNAs) are a group of small non-coding RNAs that function primarily in the post transcriptional regulation of gene expression in plants and animals. Deregulation of miRNA expression in cancer cells, including pancreatic cancer cells, is well documented, and the involvement of miRNAs in orchestrating tumor genesis and cancer progression has been recognized. This review focuses on recent reports demonstrating that miRNAs are involved in regulation of pancreatic cancer stem cells (CSCs). A number of miRNA species have been identified to be involved in regulating pancreatic CSCs, including miR-21, miR-34, miR-1246, miR-221, the miR-17-92 cluster, the miR-200 and let-7 families. Furthermore, the Notch-signaling pathway and epithelial-mesenchymal transition (EMT) process are associated with miRNA regulation of pancreatic CSCs. Given the significant contribution of CSCs to chemo-resistance and tumor progression, a better understanding of how miRNAs function in pancreatic CSCs could provide novel strategies for the development of therapeutics and diagnostics for this devastating disease." @default.
- W2579147068 created "2017-01-26" @default.
- W2579147068 creator A5013686582 @default.
- W2579147068 creator A5030347346 @default.
- W2579147068 creator A5043275768 @default.
- W2579147068 date "2017-01-21" @default.
- W2579147068 modified "2023-10-14" @default.
- W2579147068 title "microRNA regulation of human pancreatic cancer stem cells" @default.
- W2579147068 cites W1186381538 @default.
- W2579147068 cites W1473007240 @default.
- W2579147068 cites W1480706413 @default.
- W2579147068 cites W1920303762 @default.
- W2579147068 cites W1958284284 @default.
- W2579147068 cites W1964631913 @default.
- W2579147068 cites W1972670512 @default.
- W2579147068 cites W1972700706 @default.
- W2579147068 cites W1978629545 @default.
- W2579147068 cites W1980269624 @default.
- W2579147068 cites W1983991097 @default.
- W2579147068 cites W1984286055 @default.
- W2579147068 cites W1985339653 @default.
- W2579147068 cites W1996589617 @default.
- W2579147068 cites W1998196049 @default.
- W2579147068 cites W2001134763 @default.
- W2579147068 cites W2009886857 @default.
- W2579147068 cites W2012802922 @default.
- W2579147068 cites W2014691022 @default.
- W2579147068 cites W2019264784 @default.
- W2579147068 cites W2022896276 @default.
- W2579147068 cites W2026228115 @default.
- W2579147068 cites W2029738976 @default.
- W2579147068 cites W2031731215 @default.
- W2579147068 cites W2033320521 @default.
- W2579147068 cites W2040191060 @default.
- W2579147068 cites W2041343513 @default.
- W2579147068 cites W2050079849 @default.
- W2579147068 cites W2054665580 @default.
- W2579147068 cites W2056190849 @default.
- W2579147068 cites W2062575747 @default.
- W2579147068 cites W2064164438 @default.
- W2579147068 cites W2090150239 @default.
- W2579147068 cites W2090264147 @default.
- W2579147068 cites W2090648161 @default.
- W2579147068 cites W2097739264 @default.
- W2579147068 cites W2098447236 @default.
- W2579147068 cites W2102824849 @default.
- W2579147068 cites W2105549148 @default.
- W2579147068 cites W2120307929 @default.
- W2579147068 cites W2124488916 @default.
- W2579147068 cites W2136148915 @default.
- W2579147068 cites W2138343959 @default.
- W2579147068 cites W2138664009 @default.
- W2579147068 cites W2138799354 @default.
- W2579147068 cites W2140737952 @default.
- W2579147068 cites W2142421871 @default.
- W2579147068 cites W2142638537 @default.
- W2579147068 cites W2145820920 @default.
- W2579147068 cites W2146074268 @default.
- W2579147068 cites W2147807172 @default.
- W2579147068 cites W2152561870 @default.
- W2579147068 cites W2154808084 @default.
- W2579147068 cites W2158569602 @default.
- W2579147068 cites W2162674813 @default.
- W2579147068 cites W2164194749 @default.
- W2579147068 cites W2164618834 @default.
- W2579147068 cites W2165804743 @default.
- W2579147068 cites W2168584828 @default.
- W2579147068 cites W2204746834 @default.
- W2579147068 cites W2256076794 @default.
- W2579147068 cites W2276847853 @default.
- W2579147068 cites W2290593840 @default.
- W2579147068 cites W2293916969 @default.
- W2579147068 cites W2338251603 @default.
- W2579147068 cites W2412509206 @default.
- W2579147068 cites W2414312833 @default.
- W2579147068 cites W2443178263 @default.
- W2579147068 cites W2490991344 @default.
- W2579147068 cites W2508859157 @default.
- W2579147068 cites W2514305496 @default.
- W2579147068 cites W2516243475 @default.
- W2579147068 cites W2556578483 @default.
- W2579147068 cites W2597632520 @default.
- W2579147068 cites W95463455 @default.
- W2579147068 doi "https://doi.org/10.21037/sci.2017.01.01" @default.
- W2579147068 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5313281" @default.
- W2579147068 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28217707" @default.
- W2579147068 hasPublicationYear "2017" @default.
- W2579147068 type Work @default.
- W2579147068 sameAs 2579147068 @default.
- W2579147068 citedByCount "34" @default.
- W2579147068 countsByYear W25791470682017 @default.
- W2579147068 countsByYear W25791470682018 @default.
- W2579147068 countsByYear W25791470682019 @default.
- W2579147068 countsByYear W25791470682020 @default.
- W2579147068 countsByYear W25791470682021 @default.
- W2579147068 countsByYear W25791470682022 @default.
- W2579147068 crossrefType "journal-article" @default.
- W2579147068 hasAuthorship W2579147068A5013686582 @default.