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• W2579248973 abstract "This chapter explains the possibilities of the hyphenation between (U)HPLC systems with modern mass spectrometers. One central issue is the differentiation between target analysis, suspected-target and non-target screening for the individual fields of application, and kind of mass spectrometers. Method development for multicomponent target analysis using triple-quadrupole mass spectrometers with the different acquisition modes is described in detail. Especially, the influence of the data acquisition rate on the resulting number of data points is discussed in order to sensitize the reader for this important issue. For the field of screening approaches using high-resolution mass spectrometry, a common workflow to identify an unknown compound is described. Also, for this example, the influence of different acquisition modes on the number of data points per peak is discussed. At the end of this chapter, a short outlook in terms of miniaturization is given in order to show the enormous potential of this separation technique in combination with mass spectrometry." @default.
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• W2579248973 date "2017-01-06" @default.
• W2579248973 modified "2023-10-17" @default.
• W2579248973 title "Requirements of LC-Hardware for the Coupling of Different Mass Spectrometers" @default.
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• W2579248973 doi "https://doi.org/10.1002/9783527694945.ch5" @default.
• W2579248973 hasPublicationYear "2017" @default.
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