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- W2579441661 abstract "CD-HIT is one of the most popular tools for reducing sequence redundancy, and is considered to be the state-of-art method. It tries to minimise redundancy by reducing an input database into several representative sequences, under a user-defined threshold of sequence identity. We present a comprehensive assessment of the redundancy in the outputs of CD-HIT, exploring the impact of different identity thresholds and new evaluation data on the redundancy. We demonstrate that the relationship between threshold and redundancies is surprising weak. Applications of CD-HIT that set low identity threshold values also may suffer from substantial degradation in both efficiency and accuracy." @default.
- W2579441661 created "2017-01-26" @default.
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- W2579441661 date "2016-12-01" @default.
- W2579441661 modified "2023-10-12" @default.
- W2579441661 title "Evaluation of CD-HIT for constructing non-redundant databases" @default.
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- W2579441661 doi "https://doi.org/10.1109/bibm.2016.7822604" @default.
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