FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W258014774> ?p ?o ?g. }

• W258014774 endingPage "816" @default.
• W258014774 startingPage "799" @default.
• W258014774 abstract "In an in vitro autologous system, studies were carried out on the transfer of either biosynthetically-labelled [14C]Salmonella enteritidis endotoxin or [125I]Maia squinado haemocyanin from macrophages to lymphocytes.When cultured 1 hour in vitro, lymphocytes adhered to autologous macrophages, forming lymphocyte-macrophage islands (LMI).Quantitative data obtained from stained thick sections showed that 1.8 per cent of the lymphocytes had adhered to macrophages with ingested [14C]endotoxin while 0.6 per cent of the lymphocytes adhered to macrophages with ingested [125I]haemocyanin. The presence of antigen macromolecules was observed mainly within lymphocytes adhering to macrophages with ingested antigens, i.e. at the level of LMI. On the other hand, autoradiography carried out on the same thick sections, showed that 0.20 per cent of the lymphocyte population in LMI possess silver grains. High resolution autoradiographic pictures of thin sections, showed a peculiar localization of silver grains in LMI lymphocytes: about 80 per cent of the radioactivity was found within lymphocytic nuclei and the remainder either on the cellular membrane or free in the cytoplasm. The disappearance of radioactivity from the LMI-located macrophage membranes (where lymphocytes contain silver grains) as well as the regular inhibition of antigen transfer occurring after pronase treatment of the macrophage which contained ingested antigen, strongly suggest that antigen bound to macrophage membrane was transferred to lymphocytes. As pretreatment of lymphocytes with anti-Ig serum resulted in regular inhibition of antigen transfer, it appears that the Ig receptors of lymphocyte membranes play an important role in the transfer mechanism.Combined technique, i.e. autoradiography and the peroxidase method for revealing Ig bound to lymphocyte membranes, showed that silver grains occurred only within lymphocytes displaying peroxidase-positive membrane." @default.
• W258014774 created "2016-06-24" @default.
• W258014774 creator A5010209734 @default.
• W258014774 creator A5014331086 @default.
• W258014774 creator A5031471139 @default.
• W258014774 creator A5037325444 @default.
• W258014774 date "1972-12-01" @default.
• W258014774 modified "2023-10-18" @default.
• W258014774 title "Transfer of antigenic macromolecules from macrophages to lymphocytes. I. Autoradiographic and quantitative study of ( 14 C)endotoxin and ( 125 I)haemocyanin transfer." @default.
• W258014774 cites W1518493381 @default.
• W258014774 cites W1519040467 @default.
• W258014774 cites W1541896646 @default.
• W258014774 cites W1562107027 @default.
• W258014774 cites W1591322569 @default.
• W258014774 cites W1631878796 @default.
• W258014774 cites W1678372394 @default.
• W258014774 cites W185717063 @default.
• W258014774 cites W1892765114 @default.
• W258014774 cites W1893651774 @default.
• W258014774 cites W1932211265 @default.
• W258014774 cites W1938237185 @default.
• W258014774 cites W1968367408 @default.
• W258014774 cites W1969287615 @default.
• W258014774 cites W1971415079 @default.
• W258014774 cites W1972787034 @default.
• W258014774 cites W1975292724 @default.
• W258014774 cites W1976920081 @default.
• W258014774 cites W1979373626 @default.
• W258014774 cites W1985528841 @default.
• W258014774 cites W1986268777 @default.
• W258014774 cites W1989143341 @default.
• W258014774 cites W2000500156 @default.
• W258014774 cites W2001064568 @default.
• W258014774 cites W2012182952 @default.
• W258014774 cites W2020914682 @default.
• W258014774 cites W2021375302 @default.
• W258014774 cites W2023747956 @default.
• W258014774 cites W2025877524 @default.
• W258014774 cites W2042544069 @default.
• W258014774 cites W2044938314 @default.
• W258014774 cites W2045623768 @default.
• W258014774 cites W2056133730 @default.
• W258014774 cites W2066722240 @default.
• W258014774 cites W2072639905 @default.
• W258014774 cites W2073141574 @default.
• W258014774 cites W2085573122 @default.
• W258014774 cites W2094575893 @default.
• W258014774 cites W2102467546 @default.
• W258014774 cites W2114038236 @default.
• W258014774 cites W2157626085 @default.
• W258014774 cites W2169504905 @default.
• W258014774 cites W2221926917 @default.
• W258014774 cites W2254457799 @default.
• W258014774 cites W2402311135 @default.
• W258014774 cites W2408861883 @default.
• W258014774 cites W2409497896 @default.
• W258014774 cites W2411752798 @default.
• W258014774 cites W2412012761 @default.
• W258014774 cites W2414469169 @default.
• W258014774 cites W2440697764 @default.
• W258014774 cites W2460931418 @default.
• W258014774 cites W2467682003 @default.
• W258014774 cites W2950004172 @default.
• W258014774 cites W4242425577 @default.
• W258014774 cites W75673273 @default.
• W258014774 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1407999" @default.
• W258014774 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4567653" @default.
• W258014774 hasPublicationYear "1972" @default.
• W258014774 type Work @default.
• W258014774 sameAs 258014774 @default.
• W258014774 citedByCount "8" @default.
• W258014774 crossrefType "journal-article" @default.
• W258014774 hasAuthorship W258014774A5010209734 @default.
• W258014774 hasAuthorship W258014774A5014331086 @default.
• W258014774 hasAuthorship W258014774A5031471139 @default.
• W258014774 hasAuthorship W258014774A5037325444 @default.
• W258014774 hasConcept C147483822 @default.
• W258014774 hasConcept C153911025 @default.
• W258014774 hasConcept C185592680 @default.
• W258014774 hasConcept C202751555 @default.
• W258014774 hasConcept C203014093 @default.
• W258014774 hasConcept C2777761686 @default.
• W258014774 hasConcept C2779244956 @default.
• W258014774 hasConcept C2908647359 @default.
• W258014774 hasConcept C55493867 @default.
• W258014774 hasConcept C71924100 @default.
• W258014774 hasConcept C86803240 @default.
• W258014774 hasConcept C99454951 @default.
• W258014774 hasConceptScore W258014774C147483822 @default.
• W258014774 hasConceptScore W258014774C153911025 @default.
• W258014774 hasConceptScore W258014774C185592680 @default.
• W258014774 hasConceptScore W258014774C202751555 @default.
• W258014774 hasConceptScore W258014774C203014093 @default.
• W258014774 hasConceptScore W258014774C2777761686 @default.
• W258014774 hasConceptScore W258014774C2779244956 @default.
• W258014774 hasConceptScore W258014774C2908647359 @default.
• W258014774 hasConceptScore W258014774C55493867 @default.
• W258014774 hasConceptScore W258014774C71924100 @default.

• next