FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2580525033> ?p ?o ?g. }

• W2580525033 endingPage "849" @default.
• W2580525033 startingPage "843" @default.
• W2580525033 abstract "Purpose To investigate whether the Geriatric 8 (G8) and the Timed Get Up and Go Test (TGUGT) and clinical and demographic patient characteristics were associated with acute toxicity of radiation therapy and noncompliance in elderly cancer patients being irradiated with curative intent. Methods and Materials Patients were eligible if aged ≥65 years and diagnosed with breast, non-small cell lung, prostate, head and neck, rectal, or esophageal cancer, and were referred for curative radiation therapy. We recorded acute toxicity and noncompliance and identified potential predictors, including the G8 and TGUGT. Results We investigated 402 patients with a median age of 72 years (range, 65-96 years). According to the G8, 44.4% of the patients were frail. Toxicity grade ≥3 was observed in 22% of patients who were frail according to the G8 and 9.1% of patients who were not frail. The difference was 13% (confidence interval 5.2%-20%; P=.0006). According to the TGUGT 18.8% of the patients were frail; 21% of the frail according to the TGUGT developed toxicity grade ≥3, compared with 13% who were not frail. The difference was 7.3% (confidence interval −2.7% to 17%; P=.11). Overall compliance was 95%. Toxicity was most strongly associated with type of primary tumor, chemotherapy, age, and World Health Organization performance status. Compliance was associated with type of primary tumor and age. Conclusions The usefulness of the TGUGT and G8 score in daily practice seems to be limited. Type of primary tumor, chemoradiotherapy, age, and World Health Organization performance status were more strongly associated with acute toxicity. Only chemoradiotherapy and age were associated with noncompliance. Overall the compliance was very high. To allow better-informed treatment decisions, a more accurate prediction of toxicity is desirable. To investigate whether the Geriatric 8 (G8) and the Timed Get Up and Go Test (TGUGT) and clinical and demographic patient characteristics were associated with acute toxicity of radiation therapy and noncompliance in elderly cancer patients being irradiated with curative intent. Patients were eligible if aged ≥65 years and diagnosed with breast, non-small cell lung, prostate, head and neck, rectal, or esophageal cancer, and were referred for curative radiation therapy. We recorded acute toxicity and noncompliance and identified potential predictors, including the G8 and TGUGT. We investigated 402 patients with a median age of 72 years (range, 65-96 years). According to the G8, 44.4% of the patients were frail. Toxicity grade ≥3 was observed in 22% of patients who were frail according to the G8 and 9.1% of patients who were not frail. The difference was 13% (confidence interval 5.2%-20%; P=.0006). According to the TGUGT 18.8% of the patients were frail; 21% of the frail according to the TGUGT developed toxicity grade ≥3, compared with 13% who were not frail. The difference was 7.3% (confidence interval −2.7% to 17%; P=.11). Overall compliance was 95%. Toxicity was most strongly associated with type of primary tumor, chemotherapy, age, and World Health Organization performance status. Compliance was associated with type of primary tumor and age. The usefulness of the TGUGT and G8 score in daily practice seems to be limited. Type of primary tumor, chemoradiotherapy, age, and World Health Organization performance status were more strongly associated with acute toxicity. Only chemoradiotherapy and age were associated with noncompliance. Overall the compliance was very high. To allow better-informed treatment decisions, a more accurate prediction of toxicity is desirable." @default.
• W2580525033 created "2017-02-03" @default.
• W2580525033 creator A5004682204 @default.
• W2580525033 creator A5005412688 @default.
• W2580525033 creator A5019150519 @default.
• W2580525033 creator A5030540675 @default.
• W2580525033 creator A5033644402 @default.
• W2580525033 creator A5035007701 @default.
• W2580525033 creator A5035607142 @default.
• W2580525033 creator A5041507787 @default.
• W2580525033 creator A5042718146 @default.
• W2580525033 creator A5049496410 @default.
• W2580525033 creator A5049829557 @default.
• W2580525033 creator A5075566221 @default.
• W2580525033 creator A5077290589 @default.
• W2580525033 creator A5084266725 @default.
• W2580525033 creator A5090484115 @default.
• W2580525033 date "2017-07-01" @default.
• W2580525033 modified "2023-09-28" @default.
• W2580525033 title "Timed Get Up and Go Test and Geriatric 8 Scores and the Association With (Chemo-)Radiation Therapy Noncompliance and Acute Toxicity in Elderly Cancer Patients" @default.
• W2580525033 cites W1973025704 @default.
• W2580525033 cites W1974704788 @default.
• W2580525033 cites W2029384137 @default.
• W2580525033 cites W2126838184 @default.
• W2580525033 cites W2142514031 @default.
• W2580525033 cites W2150822565 @default.
• W2580525033 cites W2151595445 @default.
• W2580525033 cites W2156416775 @default.
• W2580525033 cites W2160293835 @default.
• W2580525033 cites W2167333057 @default.
• W2580525033 cites W2424391321 @default.
• W2580525033 doi "https://doi.org/10.1016/j.ijrobp.2017.01.211" @default.
• W2580525033 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28366575" @default.
• W2580525033 hasPublicationYear "2017" @default.
• W2580525033 type Work @default.
• W2580525033 sameAs 2580525033 @default.
• W2580525033 citedByCount "29" @default.
• W2580525033 countsByYear W25805250332017 @default.
• W2580525033 countsByYear W25805250332018 @default.
• W2580525033 countsByYear W25805250332019 @default.
• W2580525033 countsByYear W25805250332020 @default.
• W2580525033 countsByYear W25805250332021 @default.
• W2580525033 countsByYear W25805250332022 @default.
• W2580525033 countsByYear W25805250332023 @default.
• W2580525033 crossrefType "journal-article" @default.
• W2580525033 hasAuthorship W2580525033A5004682204 @default.
• W2580525033 hasAuthorship W2580525033A5005412688 @default.
• W2580525033 hasAuthorship W2580525033A5019150519 @default.
• W2580525033 hasAuthorship W2580525033A5030540675 @default.
• W2580525033 hasAuthorship W2580525033A5033644402 @default.
• W2580525033 hasAuthorship W2580525033A5035007701 @default.
• W2580525033 hasAuthorship W2580525033A5035607142 @default.
• W2580525033 hasAuthorship W2580525033A5041507787 @default.
• W2580525033 hasAuthorship W2580525033A5042718146 @default.
• W2580525033 hasAuthorship W2580525033A5049496410 @default.
• W2580525033 hasAuthorship W2580525033A5049829557 @default.
• W2580525033 hasAuthorship W2580525033A5075566221 @default.
• W2580525033 hasAuthorship W2580525033A5077290589 @default.
• W2580525033 hasAuthorship W2580525033A5084266725 @default.
• W2580525033 hasAuthorship W2580525033A5090484115 @default.
• W2580525033 hasConcept C116263406 @default.
• W2580525033 hasConcept C121608353 @default.
• W2580525033 hasConcept C126322002 @default.
• W2580525033 hasConcept C2776530083 @default.
• W2580525033 hasConcept C2777319248 @default.
• W2580525033 hasConcept C2778424827 @default.
• W2580525033 hasConcept C2780192828 @default.
• W2580525033 hasConcept C29730261 @default.
• W2580525033 hasConcept C44249647 @default.
• W2580525033 hasConcept C509974204 @default.
• W2580525033 hasConcept C71924100 @default.
• W2580525033 hasConceptScore W2580525033C116263406 @default.
• W2580525033 hasConceptScore W2580525033C121608353 @default.
• W2580525033 hasConceptScore W2580525033C126322002 @default.
• W2580525033 hasConceptScore W2580525033C2776530083 @default.
• W2580525033 hasConceptScore W2580525033C2777319248 @default.
• W2580525033 hasConceptScore W2580525033C2778424827 @default.
• W2580525033 hasConceptScore W2580525033C2780192828 @default.
• W2580525033 hasConceptScore W2580525033C29730261 @default.
• W2580525033 hasConceptScore W2580525033C44249647 @default.
• W2580525033 hasConceptScore W2580525033C509974204 @default.
• W2580525033 hasConceptScore W2580525033C71924100 @default.
• W2580525033 hasIssue "4" @default.
• W2580525033 hasLocation W25805250331 @default.
• W2580525033 hasLocation W25805250332 @default.
• W2580525033 hasOpenAccess W2580525033 @default.
• W2580525033 hasPrimaryLocation W25805250331 @default.
• W2580525033 hasRelatedWork W1985196274 @default.
• W2580525033 hasRelatedWork W2029344511 @default.
• W2580525033 hasRelatedWork W2107892875 @default.
• W2580525033 hasRelatedWork W2161441853 @default.
• W2580525033 hasRelatedWork W2319511888 @default.
• W2580525033 hasRelatedWork W2353454854 @default.
• W2580525033 hasRelatedWork W2377582327 @default.
• W2580525033 hasRelatedWork W2410509617 @default.
• W2580525033 hasRelatedWork W3130677002 @default.
• W2580525033 hasRelatedWork W3160081090 @default.
• W2580525033 hasVolume "98" @default.

• next