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• W2580531423 abstract "The activation or the inhibition of G-protein coupled receptors (GPCRs) implicated in the pathophysiology of neurodegenerative disorders is considered as a relevant approach for the treatment of these diseases. The modulation of the relevant GPCRs targets by positive or by negative allosteric modulators appears to be promising, the major challenge remaining the discovery of these molecules. In this review, we highlight the recent development in this field and the therapeutic potential of selected GPCRs allosteric modulators." @default.
• W2580531423 created "2017-02-03" @default.
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• W2580531423 date "2017-02-01" @default.
• W2580531423 modified "2023-09-27" @default.
• W2580531423 title "Recent advances in drug discovery of GPCR allosteric modulators for neurodegenerative disorders" @default.
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• W2580531423 doi "https://doi.org/10.1016/j.coph.2017.01.001" @default.
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