FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2580551479> ?p ?o ?g. }

• W2580551479 endingPage "10" @default.
• W2580551479 startingPage "1" @default.
• W2580551479 abstract "The history of cell culture dates back to the late nineteenth century when Wilhelm Roux for the first time successfully maintained embryonic chicken tissues in a warm saline and established the principles of cells cultivation in vitro. Since that time, scientists have endeavored to keep cells alive in vitro as model systems for experimental studies outside the body. From the very beginning it was thought that culturing cells in vitro would give a chance to find answers to many questions concerning cell biology and structure. The first human cell line was obtained in 1951 from a biopsy for cervical cancer detection. George Gey, an employee of Johns Hopkins Hospital in Baltimore, was the creator of the first human line, named HeLa after the patient Henrietta Lacks,. These cells are currently one of the most frequently used cell lines in scientific research. The HeLa cells divide rapidly and their contamination may lead to overgrowth of other cell cultures. Recent studies of the HeLa genome have confirmed the special character of these cells, resulting from altered chromosome number and structural disorder, as well as from altered expression of genes responsible for the metabolic pathways connected with DNA repair and the cell cycle. More than 70,000 articles in various scientific journals have been published on the basis of experiments using HeLa cells. There are over 50 million tons of these cells in laboratories around the world. The HeLa line has contributed to the development of techniques for conservation and culturing of cells. The use of HeLa permitted the discovery of the polio vaccine and the mechanism of HIV infection. The description of the role of HPV in the development of tumors and the discovery of telomerase, both findings made with the use of HeLa cells, have been awarded Nobel Prizes. Without a doubt, HeLa cells have significantly contributed to the advance of science, to reduction of the costs of experiments, and have enabled numerous repetitions of experiments." @default.
• W2580551479 created "2017-02-03" @default.
• W2580551479 creator A5015508604 @default.
• W2580551479 creator A5022846396 @default.
• W2580551479 date "2016-01-01" @default.
• W2580551479 modified "2023-09-28" @default.
• W2580551479 title "Odkrycie komórek HeLa początkiem rewolucji w badaniach in vitro" @default.
• W2580551479 cites W1517051009 @default.
• W2580551479 cites W1560065785 @default.
• W2580551479 cites W162187343 @default.
• W2580551479 cites W169199651 @default.
• W2580551479 cites W1886781491 @default.
• W2580551479 cites W1909009735 @default.
• W2580551479 cites W1941108988 @default.
• W2580551479 cites W1949583200 @default.
• W2580551479 cites W1966335766 @default.
• W2580551479 cites W1968208772 @default.
• W2580551479 cites W1972616856 @default.
• W2580551479 cites W1975847836 @default.
• W2580551479 cites W1979775122 @default.
• W2580551479 cites W1981369691 @default.
• W2580551479 cites W2002159402 @default.
• W2580551479 cites W2014362894 @default.
• W2580551479 cites W2015037479 @default.
• W2580551479 cites W2015236057 @default.
• W2580551479 cites W2018200116 @default.
• W2580551479 cites W2026960700 @default.
• W2580551479 cites W2035569367 @default.
• W2580551479 cites W2045970082 @default.
• W2580551479 cites W2057331628 @default.
• W2580551479 cites W2062213992 @default.
• W2580551479 cites W2070468167 @default.
• W2580551479 cites W2074131187 @default.
• W2580551479 cites W2084086160 @default.
• W2580551479 cites W2088784539 @default.
• W2580551479 cites W2089779525 @default.
• W2580551479 cites W2091744258 @default.
• W2580551479 cites W2091890751 @default.
• W2580551479 cites W2098765233 @default.
• W2580551479 cites W2099508711 @default.
• W2580551479 cites W2107094239 @default.
• W2580551479 cites W2109948920 @default.
• W2580551479 cites W2117840284 @default.
• W2580551479 cites W2121158677 @default.
• W2580551479 cites W2131517635 @default.
• W2580551479 cites W2149951876 @default.
• W2580551479 cites W2150194381 @default.
• W2580551479 cites W2312596526 @default.
• W2580551479 cites W2396150687 @default.
• W2580551479 cites W2747310579 @default.
• W2580551479 cites W91153262 @default.
• W2580551479 cites W1977394993 @default.
• W2580551479 cites W2740356810 @default.
• W2580551479 hasPublicationYear "2016" @default.
• W2580551479 type Work @default.
• W2580551479 sameAs 2580551479 @default.
• W2580551479 citedByCount "0" @default.
• W2580551479 crossrefType "journal-article" @default.
• W2580551479 hasAuthorship W2580551479A5015508604 @default.
• W2580551479 hasAuthorship W2580551479A5022846396 @default.
• W2580551479 hasConcept C1491633281 @default.
• W2580551479 hasConcept C202751555 @default.
• W2580551479 hasConcept C2777366897 @default.
• W2580551479 hasConcept C54355233 @default.
• W2580551479 hasConcept C81885089 @default.
• W2580551479 hasConcept C86803240 @default.
• W2580551479 hasConcept C95444343 @default.
• W2580551479 hasConceptScore W2580551479C1491633281 @default.
• W2580551479 hasConceptScore W2580551479C202751555 @default.
• W2580551479 hasConceptScore W2580551479C2777366897 @default.
• W2580551479 hasConceptScore W2580551479C54355233 @default.
• W2580551479 hasConceptScore W2580551479C81885089 @default.
• W2580551479 hasConceptScore W2580551479C86803240 @default.
• W2580551479 hasConceptScore W2580551479C95444343 @default.
• W2580551479 hasIssue "1" @default.
• W2580551479 hasLocation W25805514791 @default.
• W2580551479 hasOpenAccess W2580551479 @default.
• W2580551479 hasPrimaryLocation W25805514791 @default.
• W2580551479 hasVolume "65" @default.
• W2580551479 isParatext "false" @default.
• W2580551479 isRetracted "false" @default.
• W2580551479 magId "2580551479" @default.
• W2580551479 workType "article" @default.