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- W2580974037 abstract "Thromboembolic complications (TECs) are major adverse events for patients supported by left ventricular assist devices (LVADs). Despite anti-coagulation, TECs such as stroke or pump thrombosis occur in 6.5% of patients. 1 Wever-Pinzon O. Naka Y. Garan A.R. et al. National trends and outcomes in device-related thromboembolic complications and malfunction among heart transplant candidates supported with continuous-flow left ventricular assist devices in the United States. J Heart Lung Transplant. 2016; 35: 884-892 Abstract Full Text Full Text PDF PubMed Scopus (16) Google Scholar Risk of TECs increases with longer duration of device support, and the risk is likely greater in patients receiving LVADs as destination therapy. Surgical or percutaneous occlusion of the left atrial appendage (LAA) reduces TECs in patients with atrial fibrillation. 2 Reddy V.Y. Sievert H. Halperin J. et al. Percutaneous left atrial appendage closure vs warfarin for atrial fibrillation: a randomized clinical trial. JAMA. 2014; 312: 1988-1998 Crossref PubMed Scopus (591) Google Scholar , 3 Berti S. Pastormerlo L.E. Rezzaghi M. et al. Left atrial appendage occlusion in high-risk patients with non-valvular atrial fibrillation. Heart. 2016; 102: 1969-1973 Crossref PubMed Scopus (26) Google Scholar The LAA may also be a source of thromboembolism for patients with systolic heart failure, including patients in sinus rhythm. 4 Bakalli A. Georgievska-Ismail L.J. Zanteva-Naumoska M. et al. Predictors of left atrial appendage thrombus in heart failure patients at sinus rhythm. Eur Heart J. 2013; 34: P2189 Crossref Google Scholar We hypothesized that surgical occlusion of the LAA could reduce TECs in patients with an LVAD. In this study, we report our experience with left atrial appendage occlusion (LAAO) in patients with an LVAD implanted as destination therapy." @default.
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- W2580974037 date "2017-05-01" @default.
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- W2580974037 title "Surgical occlusion of the left atrial appendage and thromboembolic complications in patients with left ventricular assist devices" @default.
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- W2580974037 doi "https://doi.org/10.1016/j.healun.2017.01.1297" @default.
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