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- W2582152285 abstract "In this study, we aimed to assess the levels of B cell activating factor from the tumor necrosis factor family (BAFF) and a proliferation-inducing ligand (APRIL) in cerebrospinal fluid (CSF) of patients with anti–N-methyl-d-aspartate receptor (NMDAR) encephalitis and determine their correlation with clinical outcome. BAFF and APRIL concentrations in CSF and serum from 40 patients with anti-NMDAR encephalitis and 20 controls were measured by enzyme-linked immunosorbent assay (ELISA). Compared with controls, the levels of both BAFF and APRIL in CSF were significantly increased in patients with anti-NMDAR encephalitis (p < 0.001 and p < 0.001). Patients with unfavorable outcome had higher levels of BAFF and APRIL in CSF than those who had favorable outcome (p < 0.05 and p < 0.05). BAFF and APRIL levels in CSF were elevated and associated with clinical outcome in patients with anti-NMDAR encephalitis, indicating that they may be valuable biomarkers to this disease." @default.
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- W2582152285 date "2017-04-01" @default.
- W2582152285 modified "2023-09-28" @default.
- W2582152285 title "Raised cerebrospinal fluid BAFF and APRIL levels in anti- N -methyl- d -aspartate receptor encephalitis: Correlation with clinical outcome" @default.
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- W2582152285 doi "https://doi.org/10.1016/j.jneuroim.2017.01.012" @default.
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