Matches in SemOpenAlex for { <https://semopenalex.org/work/W2582183744> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2582183744 abstract "A143 Inflammation plays an important role in colon carcinogenesis and can be modified by diet. To identify bioactive food components for colon cancer prevention and their molecular targets, we developed a colon carcinogenesis model using azoxymethane(AOM)/dextran sodium sulfate(DSS)-induced FVB mice. At 6 weeks of age, mice were injected intraperitoneally with AOM (10 mg/kg body weight). Mice then received for 1 week as drinking water 0 or 1% DSS dissolved in distilled water (1 and 4 weeks after AOM injection). One week after the first DSS cycle, some mice were switched from an AIN-93G diet to one enriched with 85 mg of the garlic metabolite diallyl disulfide/kg diet. Mice were sacrificed at multiple time points to coincide with early stages of colon carcinogenesis. RNA was isolated from scraped colon tissue, and transcript levels of 84 genes involved in mediating the immune response during inflammation were measured using real-time qPCR. The AOM/DSS-induced mice showed progression through stages of colon carcinogenesis. Dietary diallyl disulfide attenuated tumor multiplicity when fed after AOM/DSS-induction. Expression of most inflammation-associated genes increased gradually with progression through stages of colon carcinogenesis and with tumor multiplicity. Dietary diallyl disulfide significantly decreased (P" @default.
- W2582183744 created "2017-02-03" @default.
- W2582183744 creator A5000681392 @default.
- W2582183744 creator A5013542315 @default.
- W2582183744 creator A5034720305 @default.
- W2582183744 creator A5048962207 @default.
- W2582183744 creator A5052587383 @default.
- W2582183744 creator A5078169073 @default.
- W2582183744 date "2007-12-01" @default.
- W2582183744 modified "2023-09-23" @default.
- W2582183744 title "Inflammation-associated genes as potential molecular targets for dietary prevention of colon carcinogenesis in an AOM-DSS mouse model" @default.
- W2582183744 hasPublicationYear "2007" @default.
- W2582183744 type Work @default.
- W2582183744 sameAs 2582183744 @default.
- W2582183744 citedByCount "0" @default.
- W2582183744 crossrefType "journal-article" @default.
- W2582183744 hasAuthorship W2582183744A5000681392 @default.
- W2582183744 hasAuthorship W2582183744A5013542315 @default.
- W2582183744 hasAuthorship W2582183744A5034720305 @default.
- W2582183744 hasAuthorship W2582183744A5048962207 @default.
- W2582183744 hasAuthorship W2582183744A5052587383 @default.
- W2582183744 hasAuthorship W2582183744A5078169073 @default.
- W2582183744 hasConcept C121608353 @default.
- W2582183744 hasConcept C126322002 @default.
- W2582183744 hasConcept C190283241 @default.
- W2582183744 hasConcept C203014093 @default.
- W2582183744 hasConcept C2776488830 @default.
- W2582183744 hasConcept C2776914184 @default.
- W2582183744 hasConcept C2778452354 @default.
- W2582183744 hasConcept C502942594 @default.
- W2582183744 hasConcept C526805850 @default.
- W2582183744 hasConcept C55493867 @default.
- W2582183744 hasConcept C555283112 @default.
- W2582183744 hasConcept C71924100 @default.
- W2582183744 hasConcept C86803240 @default.
- W2582183744 hasConcept C8891405 @default.
- W2582183744 hasConceptScore W2582183744C121608353 @default.
- W2582183744 hasConceptScore W2582183744C126322002 @default.
- W2582183744 hasConceptScore W2582183744C190283241 @default.
- W2582183744 hasConceptScore W2582183744C203014093 @default.
- W2582183744 hasConceptScore W2582183744C2776488830 @default.
- W2582183744 hasConceptScore W2582183744C2776914184 @default.
- W2582183744 hasConceptScore W2582183744C2778452354 @default.
- W2582183744 hasConceptScore W2582183744C502942594 @default.
- W2582183744 hasConceptScore W2582183744C526805850 @default.
- W2582183744 hasConceptScore W2582183744C55493867 @default.
- W2582183744 hasConceptScore W2582183744C555283112 @default.
- W2582183744 hasConceptScore W2582183744C71924100 @default.
- W2582183744 hasConceptScore W2582183744C86803240 @default.
- W2582183744 hasConceptScore W2582183744C8891405 @default.
- W2582183744 hasOpenAccess W2582183744 @default.
- W2582183744 hasRelatedWork W1624903700 @default.
- W2582183744 hasRelatedWork W178134299 @default.
- W2582183744 hasRelatedWork W2002945070 @default.
- W2582183744 hasRelatedWork W2021628686 @default.
- W2582183744 hasRelatedWork W2041838266 @default.
- W2582183744 hasRelatedWork W2066544971 @default.
- W2582183744 hasRelatedWork W2069904167 @default.
- W2582183744 hasRelatedWork W2096541155 @default.
- W2582183744 hasRelatedWork W2097077016 @default.
- W2582183744 hasRelatedWork W2124052496 @default.
- W2582183744 hasRelatedWork W2215682934 @default.
- W2582183744 hasRelatedWork W2268653494 @default.
- W2582183744 hasRelatedWork W2482405646 @default.
- W2582183744 hasRelatedWork W2742519607 @default.
- W2582183744 hasRelatedWork W2885673575 @default.
- W2582183744 hasRelatedWork W2895115778 @default.
- W2582183744 hasRelatedWork W2962099006 @default.
- W2582183744 hasRelatedWork W3003738121 @default.
- W2582183744 hasRelatedWork W3026385292 @default.
- W2582183744 hasRelatedWork W3146673194 @default.
- W2582183744 hasVolume "16" @default.
- W2582183744 isParatext "false" @default.
- W2582183744 isRetracted "false" @default.
- W2582183744 magId "2582183744" @default.
- W2582183744 workType "article" @default.