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- W2582402173 abstract "The present chapter attempts to outline the rules that govern dendritic spine formation, plasticity, and elimination in relation to memory functions in the brain. The striking heterogeneity of spine morphologies on different types of neurons, as well as among adjacent spines in the same dendritic branch complicates this analysis. Major issues concerning the relationship between the morphology of dendritic spines and memory mechanisms and the functional, neuronal network relevance of such parameters remain unsettled; for example, what are the immediate and long-lasting changes in electrical properties of dendritic spines and their parent neurons following exposure to plasticity-producing stimulation? Are there different structural correlates for different classes of memories (e.g., episodic, semantic, motor)? What happens to the structural change when a memory is removed or moved from one brain area to another? Can we improve memory by changing the structure? A growing body of research indicates that indeed, dendritic spines are the best morphological correlates of different types of memories, in different brain regions. In this chapter, we will outline the main molecular properties of dendritic spines, as well as the changes observed in the hippocampus, amygdala, and cortical structures in relations to different forms of learning and memory." @default.
- W2582402173 created "2017-02-03" @default.
- W2582402173 creator A5028740326 @default.
- W2582402173 creator A5046058862 @default.
- W2582402173 date "2017-01-01" @default.
- W2582402173 modified "2023-09-27" @default.
- W2582402173 title "Dendritic Spine Plasticity and Memory Formation" @default.
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