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- W2582505655 abstract "Tuberculous pericarditis remains one of the most feared manifestations of extra-pulmonary tuberculosis (TB). The relatively high morbidity and mortality rates associated with the condition arise via two distinct mechanisms. The first is related to the combined impact of the virulence of Mycobacterium tuberculosis (MTb) itself and TB-induced dysregulated immune responses in both HIV-positive and -negative individuals, resulting in disseminated infection, multi-organ involvement, and prolonged acute infection. The second mechanism is related to compressive pericardial disease (cardiac tamponade, effusive constrictive pericarditis and constrictive pericarditis), which can cause significant compromise of cardiovascular function." @default.
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- W2582505655 date "2016-12-15" @default.
- W2582505655 modified "2023-10-18" @default.
- W2582505655 title "The importance of perseverance, pilot studies and the search for effective adjuvant therapies in the management of tuberculous pericarditis." @default.
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