Matches in SemOpenAlex for { <https://semopenalex.org/work/W2582783508> ?p ?o ?g. }
- W2582783508 endingPage "156" @default.
- W2582783508 startingPage "140" @default.
- W2582783508 abstract "Although our understanding of the relationship between posttraumatic stress disorder (PTSD), brain structure and function, neural networks, stress-related systems, and genetics is growing, there is considerably less attention given to which biological markers predict evidence-based PTSD psychotherapy outcomes. Our systematic PRISMA-informed review of 20 studies examined biomarkers as predictors of evidence-based PTSD psychotherapy outcomes. Results provide preliminary evidence that specific structural and functional neural systems (involved in information processing), glucocorticoid sensitivity and metabolism (part of the hypothalamic–pituitary–adrenal axis and the response to stress), heart rate (involved with fear habituation), gene methylation, and certain genotypes (associated with serotonin and glucocorticoids) predicted positive response to PTSD treatment. These pre-treatment biomarkers are associated with processes integral to PTSD treatment, such as those affecting fear learning and extinction, cognitive restructuring, information processing, emotional processing, and interoceptive monitoring. Identifying pre-treatment biomarkers that predict treatment response may offer insight into the mechanisms of psychological treatment, provide a foundation for improving the pharmaceutical augmentation of treatment, and inform treatment matching." @default.
- W2582783508 created "2017-02-03" @default.
- W2582783508 creator A5004217891 @default.
- W2582783508 creator A5021068945 @default.
- W2582783508 creator A5022827932 @default.
- W2582783508 creator A5023892991 @default.
- W2582783508 creator A5045963082 @default.
- W2582783508 creator A5051299058 @default.
- W2582783508 creator A5060364399 @default.
- W2582783508 creator A5088332343 @default.
- W2582783508 date "2017-04-01" @default.
- W2582783508 modified "2023-10-18" @default.
- W2582783508 title "Pretreatment biomarkers predicting PTSD psychotherapy outcomes: A systematic review" @default.
- W2582783508 cites W1525373779 @default.
- W2582783508 cites W1564331199 @default.
- W2582783508 cites W1577271808 @default.
- W2582783508 cites W1600390011 @default.
- W2582783508 cites W1883268346 @default.
- W2582783508 cites W1954971303 @default.
- W2582783508 cites W1957609010 @default.
- W2582783508 cites W1964308211 @default.
- W2582783508 cites W1965591468 @default.
- W2582783508 cites W1965772852 @default.
- W2582783508 cites W1965862719 @default.
- W2582783508 cites W1968696218 @default.
- W2582783508 cites W1971041158 @default.
- W2582783508 cites W1972110549 @default.
- W2582783508 cites W1978316801 @default.
- W2582783508 cites W1981030752 @default.
- W2582783508 cites W1986459850 @default.
- W2582783508 cites W1989045560 @default.
- W2582783508 cites W1990652217 @default.
- W2582783508 cites W1991924547 @default.
- W2582783508 cites W1992582497 @default.
- W2582783508 cites W1996158088 @default.
- W2582783508 cites W1999405675 @default.
- W2582783508 cites W2000592388 @default.
- W2582783508 cites W2001261239 @default.
- W2582783508 cites W2001362807 @default.
- W2582783508 cites W2005501262 @default.
- W2582783508 cites W2006486060 @default.
- W2582783508 cites W2010545823 @default.
- W2582783508 cites W2011447821 @default.
- W2582783508 cites W2023657726 @default.
- W2582783508 cites W2024994042 @default.
- W2582783508 cites W2029526731 @default.
- W2582783508 cites W2042430625 @default.
- W2582783508 cites W2046796005 @default.
- W2582783508 cites W2047217999 @default.
- W2582783508 cites W2050042714 @default.
- W2582783508 cites W2056505484 @default.
- W2582783508 cites W2056786635 @default.
- W2582783508 cites W2061428806 @default.
- W2582783508 cites W2062945215 @default.
- W2582783508 cites W2064756281 @default.
- W2582783508 cites W2064874019 @default.
- W2582783508 cites W2066642195 @default.
- W2582783508 cites W2068392981 @default.
- W2582783508 cites W2071057820 @default.
- W2582783508 cites W2071580102 @default.
- W2582783508 cites W2072290882 @default.
- W2582783508 cites W2080641591 @default.
- W2582783508 cites W2082574777 @default.
- W2582783508 cites W2087060903 @default.
- W2582783508 cites W2087582210 @default.
- W2582783508 cites W2087890860 @default.
- W2582783508 cites W2089846979 @default.
- W2582783508 cites W2089872340 @default.
- W2582783508 cites W2094286961 @default.
- W2582783508 cites W2099136954 @default.
- W2582783508 cites W2100532508 @default.
- W2582783508 cites W2101688601 @default.
- W2582783508 cites W2106095564 @default.
- W2582783508 cites W2107069925 @default.
- W2582783508 cites W2109795817 @default.
- W2582783508 cites W2111862372 @default.
- W2582783508 cites W2115274607 @default.
- W2582783508 cites W2121878996 @default.
- W2582783508 cites W2122382299 @default.
- W2582783508 cites W2126179831 @default.
- W2582783508 cites W2127573696 @default.
- W2582783508 cites W2128740341 @default.
- W2582783508 cites W2130135754 @default.
- W2582783508 cites W2130417276 @default.
- W2582783508 cites W2130838343 @default.
- W2582783508 cites W2134305330 @default.
- W2582783508 cites W2137752381 @default.
- W2582783508 cites W2139732540 @default.
- W2582783508 cites W2142213531 @default.
- W2582783508 cites W2144325046 @default.
- W2582783508 cites W2144494899 @default.
- W2582783508 cites W2144706276 @default.
- W2582783508 cites W2145819353 @default.
- W2582783508 cites W2147351252 @default.
- W2582783508 cites W2151027504 @default.
- W2582783508 cites W2152791743 @default.
- W2582783508 cites W2155439641 @default.
- W2582783508 cites W2156188967 @default.