Matches in SemOpenAlex for { <https://semopenalex.org/work/W2584759432> ?p ?o ?g. }
- W2584759432 endingPage "134" @default.
- W2584759432 startingPage "125" @default.
- W2584759432 abstract "Objective: Compare enzymatic debridement using clostridial collagenase ointment (CCO) with autolytic debridement using medicinal honey in the hospital outpatient setting for treating pressure ulcers (PUs). Approach: Retrospective deidentified electronic health records from 2007-2013 were extracted from the U.S. Wound Registry. Propensity score matching followed by multivariable analyses was used to adjust for selection bias and assess treatment effects comparing CCO-treated versus honey-treated PUs. Key outcomes included 100% granulation and epithelialization at 1 year. Results: Five hundred seventeen CCO-treated PUs (446 patients) were matched to corresponding honey-treated PUs (341 patients). The majority of PUs were stage III (CCO 56%, honey 55%). CCO users had significantly fewer total visits (9.1 vs. 12.6; p < 0.001), fewer total selective sharp debridements (2.7 vs. 4.4; p < 0.001), and fewer PUs receiving negative pressure wound therapy (29% vs. 38%; p = 0.002) compared with honey. Innovation: CCO-treated PUs were 38% more likely to achieve 100% granulation compared to honey-treated PUs at 1 year, p = 0.018. Mean days to 100% granulation were significantly lower for CCO-treated PUs (255 vs. 282 days, p < 0.001). CCO-treated PUs were 47% (p = 0.024) more likely to epithelialize at 1 year compared to PUs treated with honey. Mean days to epithelialization were significantly lower for PUs treated with CCO at 1 year (288 vs. 308 days; p = 0.011). Conclusion: All stages of PUs treated with CCO achieved faster rates of granulation and subsequent epithelialization compared to PUs treated with medicinal honey as measured by real-world data collected in the hospital outpatient department care setting." @default.
- W2584759432 created "2017-02-10" @default.
- W2584759432 creator A5007314209 @default.
- W2584759432 creator A5038380665 @default.
- W2584759432 creator A5040703734 @default.
- W2584759432 creator A5066307156 @default.
- W2584759432 creator A5070755970 @default.
- W2584759432 creator A5086318602 @default.
- W2584759432 date "2017-04-01" @default.
- W2584759432 modified "2023-09-27" @default.
- W2584759432 title "Comparative Effectiveness of Clostridial Collagenase Ointment to Medicinal Honey for Treatment of Pressure Ulcers" @default.
- W2584759432 cites W1277182343 @default.
- W2584759432 cites W14293889 @default.
- W2584759432 cites W1524660345 @default.
- W2584759432 cites W165446420 @default.
- W2584759432 cites W1672026537 @default.
- W2584759432 cites W1805985328 @default.
- W2584759432 cites W187776779 @default.
- W2584759432 cites W1967273874 @default.
- W2584759432 cites W1970251084 @default.
- W2584759432 cites W1971211075 @default.
- W2584759432 cites W1976956702 @default.
- W2584759432 cites W1985850653 @default.
- W2584759432 cites W1989424483 @default.
- W2584759432 cites W1998174172 @default.
- W2584759432 cites W2003770543 @default.
- W2584759432 cites W2060420558 @default.
- W2584759432 cites W2066382922 @default.
- W2584759432 cites W2068668798 @default.
- W2584759432 cites W2080049979 @default.
- W2584759432 cites W2088821036 @default.
- W2584759432 cites W2111665492 @default.
- W2584759432 cites W2120033284 @default.
- W2584759432 cites W2121690051 @default.
- W2584759432 cites W2123138690 @default.
- W2584759432 cites W2127814906 @default.
- W2584759432 cites W2183588046 @default.
- W2584759432 cites W2188850569 @default.
- W2584759432 cites W2220907381 @default.
- W2584759432 cites W236706659 @default.
- W2584759432 cites W2394699653 @default.
- W2584759432 cites W2470364646 @default.
- W2584759432 cites W4213358921 @default.
- W2584759432 cites W4233823288 @default.
- W2584759432 cites W4234300503 @default.
- W2584759432 cites W2992354073 @default.
- W2584759432 doi "https://doi.org/10.1089/wound.2016.0720" @default.
- W2584759432 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5385575" @default.
- W2584759432 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28451469" @default.
- W2584759432 hasPublicationYear "2017" @default.
- W2584759432 type Work @default.
- W2584759432 sameAs 2584759432 @default.
- W2584759432 citedByCount "10" @default.
- W2584759432 countsByYear W25847594322017 @default.
- W2584759432 countsByYear W25847594322018 @default.
- W2584759432 countsByYear W25847594322019 @default.
- W2584759432 countsByYear W25847594322020 @default.
- W2584759432 countsByYear W25847594322022 @default.
- W2584759432 crossrefType "journal-article" @default.
- W2584759432 hasAuthorship W2584759432A5007314209 @default.
- W2584759432 hasAuthorship W2584759432A5038380665 @default.
- W2584759432 hasAuthorship W2584759432A5040703734 @default.
- W2584759432 hasAuthorship W2584759432A5066307156 @default.
- W2584759432 hasAuthorship W2584759432A5070755970 @default.
- W2584759432 hasAuthorship W2584759432A5086318602 @default.
- W2584759432 hasBestOaLocation W25847594321 @default.
- W2584759432 hasConcept C126322002 @default.
- W2584759432 hasConcept C141071460 @default.
- W2584759432 hasConcept C2776055305 @default.
- W2584759432 hasConcept C2777438270 @default.
- W2584759432 hasConcept C2780269544 @default.
- W2584759432 hasConcept C71924100 @default.
- W2584759432 hasConceptScore W2584759432C126322002 @default.
- W2584759432 hasConceptScore W2584759432C141071460 @default.
- W2584759432 hasConceptScore W2584759432C2776055305 @default.
- W2584759432 hasConceptScore W2584759432C2777438270 @default.
- W2584759432 hasConceptScore W2584759432C2780269544 @default.
- W2584759432 hasConceptScore W2584759432C71924100 @default.
- W2584759432 hasIssue "4" @default.
- W2584759432 hasLocation W25847594321 @default.
- W2584759432 hasLocation W25847594322 @default.
- W2584759432 hasLocation W25847594323 @default.
- W2584759432 hasLocation W25847594324 @default.
- W2584759432 hasOpenAccess W2584759432 @default.
- W2584759432 hasPrimaryLocation W25847594321 @default.
- W2584759432 hasRelatedWork W2068711076 @default.
- W2584759432 hasRelatedWork W2082341184 @default.
- W2584759432 hasRelatedWork W2098670130 @default.
- W2584759432 hasRelatedWork W2170478492 @default.
- W2584759432 hasRelatedWork W2223461400 @default.
- W2584759432 hasRelatedWork W2362183612 @default.
- W2584759432 hasRelatedWork W2366666323 @default.
- W2584759432 hasRelatedWork W2369162477 @default.
- W2584759432 hasRelatedWork W2377724491 @default.
- W2584759432 hasRelatedWork W2897277731 @default.
- W2584759432 hasVolume "6" @default.
- W2584759432 isParatext "false" @default.
- W2584759432 isRetracted "false" @default.