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- W2585261570 abstract "In recent times, allergy has become a financial, physical and psychological burden to the society as a whole. Allergic reactions can result in life-threatening situations causing morbidity and high economic cost. Therefore, more effective reagents are needed for allergy treatment. Omega-6 fatty acids have gained attention in allergic studies mainly due to their inflammatory properties. Literature suggests that a causal relationship exists between the intake of omega-6 fatty acids such as DPA and AA and atopic individuals suffering from allergies. In an allergic cascade, cytokines IL-4 and IL-13 bind to IL-4 receptor (IL-4R), which activates the STAT6 phosphorylation pathway leading to gene activation of allergen-specific IgE production by B cells. Consequently, IgE production leads to clinical symptoms of allergy. The overall aim of this study is to characterise DPA and AA and their effects on IgE production." @default.
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- W2585261570 date "2014-01-01" @default.
- W2585261570 modified "2023-09-23" @default.
- W2585261570 title "Discovering the effects of omega-6 fatty acids on allergy using a HEK-Blue cell line" @default.
- W2585261570 hasPublicationYear "2014" @default.
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