FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2585381331> ?p ?o ?g. }

• W2585381331 endingPage "128" @default.
• W2585381331 startingPage "123" @default.
• W2585381331 abstract "Reactive oxygen species (ROS) generation is one of the mechanisms underlying noise-induced hearing loss (NIHL). Manganese superoxide dismutase (Mn-SOD), an antioxidant enzyme acting within the mitochondria, converts toxic superoxide to hydrogen peroxide. We investigated the role of Mn-SOD in NIHL by examining the extent of hearing loss and hair cell damage after noise exposure in C57BL/6 wild-type (WT) mice and Mn-SOD heterozygous knockout (HET) mice (n=6 each). Both HET and WT mice were exposed to 120dB sound pressure level at 4kHz octave band noise for 4h. Auditory brainstem responses (ABRs) were used to evaluate hearing thresholds before noise exposure, and at 1h, and 1, 3, 7, and 14days after exposure. The mice were euthanized 14days after noise exposure for examination of the cochlear pathology. Mean ABR thresholds were similarly elevated at all frequencies in both groups 1h after noise exposure, but were significantly worse, particularly at 4kHz, on post-noise exposure days 7 and 14 in HET mice compared with WT mice. Outer hair cell damage was significantly greater in all cochlear turns in HET mice compared with WT mice. Collectively, these findings suggest that Mn-SOD plays an important role in protecting the cochlea from noise-induced damage." @default.
• W2585381331 created "2017-02-10" @default.
• W2585381331 creator A5000861547 @default.
• W2585381331 creator A5018480613 @default.
• W2585381331 creator A5037942698 @default.
• W2585381331 creator A5052789879 @default.
• W2585381331 creator A5055325335 @default.
• W2585381331 creator A5056991066 @default.
• W2585381331 creator A5083435811 @default.
• W2585381331 date "2017-03-01" @default.
• W2585381331 modified "2023-10-03" @default.
• W2585381331 title "Manganese superoxide dismutase influences the extent of noise-induced hearing loss in mice" @default.
• W2585381331 cites W1965891907 @default.
• W2585381331 cites W1985499785 @default.
• W2585381331 cites W2004351969 @default.
• W2585381331 cites W2010929507 @default.
• W2585381331 cites W2028135910 @default.
• W2585381331 cites W204223750 @default.
• W2585381331 cites W2042637324 @default.
• W2585381331 cites W2065953416 @default.
• W2585381331 cites W2066207377 @default.
• W2585381331 cites W2075639702 @default.
• W2585381331 cites W2076485464 @default.
• W2585381331 cites W2094655287 @default.
• W2585381331 cites W2113675388 @default.
• W2585381331 cites W2146980664 @default.
• W2585381331 cites W2156706856 @default.
• W2585381331 cites W4256429127 @default.
• W2585381331 doi "https://doi.org/10.1016/j.neulet.2017.02.003" @default.
• W2585381331 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28163078" @default.
• W2585381331 hasPublicationYear "2017" @default.
• W2585381331 type Work @default.
• W2585381331 sameAs 2585381331 @default.
• W2585381331 citedByCount "26" @default.
• W2585381331 countsByYear W25853813312018 @default.
• W2585381331 countsByYear W25853813312019 @default.
• W2585381331 countsByYear W25853813312020 @default.
• W2585381331 countsByYear W25853813312021 @default.
• W2585381331 countsByYear W25853813312022 @default.
• W2585381331 countsByYear W25853813312023 @default.
• W2585381331 crossrefType "journal-article" @default.
• W2585381331 hasAuthorship W2585381331A5000861547 @default.
• W2585381331 hasAuthorship W2585381331A5018480613 @default.
• W2585381331 hasAuthorship W2585381331A5037942698 @default.
• W2585381331 hasAuthorship W2585381331A5052789879 @default.
• W2585381331 hasAuthorship W2585381331A5055325335 @default.
• W2585381331 hasAuthorship W2585381331A5056991066 @default.
• W2585381331 hasAuthorship W2585381331A5083435811 @default.
• W2585381331 hasConcept C115961682 @default.
• W2585381331 hasConcept C126322002 @default.
• W2585381331 hasConcept C134018914 @default.
• W2585381331 hasConcept C154945302 @default.
• W2585381331 hasConcept C16685009 @default.
• W2585381331 hasConcept C170493617 @default.
• W2585381331 hasConcept C181199279 @default.
• W2585381331 hasConcept C182704531 @default.
• W2585381331 hasConcept C185592680 @default.
• W2585381331 hasConcept C2775838275 @default.
• W2585381331 hasConcept C2778004101 @default.
• W2585381331 hasConcept C2778585322 @default.
• W2585381331 hasConcept C2779356876 @default.
• W2585381331 hasConcept C2780130748 @default.
• W2585381331 hasConcept C2780493683 @default.
• W2585381331 hasConcept C2780795997 @default.
• W2585381331 hasConcept C3018332767 @default.
• W2585381331 hasConcept C41008148 @default.
• W2585381331 hasConcept C48349386 @default.
• W2585381331 hasConcept C548259974 @default.
• W2585381331 hasConcept C55493867 @default.
• W2585381331 hasConcept C71924100 @default.
• W2585381331 hasConcept C86803240 @default.
• W2585381331 hasConcept C99498987 @default.
• W2585381331 hasConceptScore W2585381331C115961682 @default.
• W2585381331 hasConceptScore W2585381331C126322002 @default.
• W2585381331 hasConceptScore W2585381331C134018914 @default.
• W2585381331 hasConceptScore W2585381331C154945302 @default.
• W2585381331 hasConceptScore W2585381331C16685009 @default.
• W2585381331 hasConceptScore W2585381331C170493617 @default.
• W2585381331 hasConceptScore W2585381331C181199279 @default.
• W2585381331 hasConceptScore W2585381331C182704531 @default.
• W2585381331 hasConceptScore W2585381331C185592680 @default.
• W2585381331 hasConceptScore W2585381331C2775838275 @default.
• W2585381331 hasConceptScore W2585381331C2778004101 @default.
• W2585381331 hasConceptScore W2585381331C2778585322 @default.
• W2585381331 hasConceptScore W2585381331C2779356876 @default.
• W2585381331 hasConceptScore W2585381331C2780130748 @default.
• W2585381331 hasConceptScore W2585381331C2780493683 @default.
• W2585381331 hasConceptScore W2585381331C2780795997 @default.
• W2585381331 hasConceptScore W2585381331C3018332767 @default.
• W2585381331 hasConceptScore W2585381331C41008148 @default.
• W2585381331 hasConceptScore W2585381331C48349386 @default.
• W2585381331 hasConceptScore W2585381331C548259974 @default.
• W2585381331 hasConceptScore W2585381331C55493867 @default.
• W2585381331 hasConceptScore W2585381331C71924100 @default.
• W2585381331 hasConceptScore W2585381331C86803240 @default.
• W2585381331 hasConceptScore W2585381331C99498987 @default.
• W2585381331 hasLocation W25853813311 @default.
• W2585381331 hasLocation W25853813312 @default.

• next