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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2585484755> ?p ?o ?g. }

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• W2585484755 abstract "MicroRNAs (miRNAs) play important roles in the pathogenesis of many types of cancers by negatively regulating gene expression at posttranscriptional level. Here, we identified that miR-599 is up-regulated in non-small cell lung cancer (NSCLC) patients. It promoted NSCLC cell proliferation by negatively regulating SATB2. In NSCLC cell lines, CCK-8 proliferation assay indicated that the cell proliferation is promoted by miR-599 mimics. Transwell assay showed that miR-599 mimics promoted the invasion and migration of NSCLC cells. Luciferase assays confirmed that miR-599 directly binds to the 3'untranslated region of SATB2, and western blotting showed that miR-599 suppresses the expression of SATB2 at the protein level. This study indicates that miR-599 promotes proliferation and invasion of NSCLC cell lines via SATB2. The miR-599 may represent a potential therapeutic target for NSCLC treatment." @default.
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• W2585484755 date "2017-03-01" @default.
• W2585484755 modified "2023-10-14" @default.
• W2585484755 title "RETRACTED: The miR-599 promotes non-small cell lung cancer cell invasion via SATB2" @default.
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• W2585484755 doi "https://doi.org/10.1016/j.bbrc.2017.02.005" @default.
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