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- W2585778255 abstract "Objective To explore the efficacy of different doses of mifepristone in the treatment of uterine fibroids. Methods 96 patients with uterine fibroids treated in Sanya Traditional Chinese Medicine Hospital from April 2014 to April 2015 were selected. Using random number table,the patients were divided into the high-dose group and small-dose group,with 48 patients in each group. Patients in high-dose group received 25 mg mifepristone once daily,while patients in small-dose group received 12. 5 mg mifepristone once daily. The efficacy was compared between the two groups. Results The total effective rate has no statistical significance between the two groups( P > 0. 05). Patients in high-dose group had a significantly higher incidence of adverse drug reactions than that in low-dose group( P < 0. 05). Levels of folliclestimulating hormone( FSH),luteinising hormone( LH),estradiol( E2),progesterone( P) in small-dose group after treatment was significantly lower than those of high-dose group( P < 0. 05). After treatment,menstruation and menstrual volume in small dose group was significantly higher than that in high dose group( P < 0. 05). Conclusion 12. 5 mg mifepristone once daily is a safe and effective for uterine fibroids." @default.
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- W2585778255 date "2016-01-01" @default.
- W2585778255 modified "2023-09-27" @default.
- W2585778255 title "Efficacy of different doses of mifepristone in the treatment of uterine fibroids" @default.
- W2585778255 hasPublicationYear "2016" @default.
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