FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2586136145> ?p ?o ?g. }

• W2586136145 endingPage "743" @default.
• W2586136145 startingPage "734" @default.
• W2586136145 abstract "A transition-metal (TM)-free and halogen-free NaOtBu-mediated oxidative cross-coupling between the sp3 C-H bond of oxindoles and sp2 C-H bond of nitroarenes has been developed to access 3-aryl substituted and 3,3-aryldisubstituted oxindoles in DMSO at room temperature in a short time. Interestingly, the sp3 C-H bond of oxindoles could also react with styrene under TM-free conditions for the practical synthesis of quaternary 3,3-disubstituted oxindoles. The synthesized 3-oxindoles have also been further transformed into advanced heterocycles, that is, benzofuroindoles, indoloindoles, and substituted indoles. Mechanistic experiments of the reaction suggests the formation of an anion intermediate from the sp3 C-H bond of oxindole by tert-butoxide base in DMSO. The addition of nitrobenzene to the in-situ generated carbanion leads to the 3-(nitrophenyl)oxindolyl carbanion in DMSO which is subsequently oxidized to 3-(nitro-aryl) oxindole by DMSO." @default.
• W2586136145 created "2017-02-17" @default.
• W2586136145 creator A5022339470 @default.
• W2586136145 creator A5038756367 @default.
• W2586136145 creator A5041944543 @default.
• W2586136145 creator A5048002686 @default.
• W2586136145 date "2017-03-02" @default.
• W2586136145 modified "2023-10-12" @default.
• W2586136145 title "Transition-metal-free Chemoselective Oxidative C−C Coupling of the sp³C−H Bond of Oxindoles with Arenes and Addition to Alkene: Synthesis of 3-Aryl Oxindoles, and Benzofuro- and Indoloindoles" @default.
• W2586136145 cites W1964658948 @default.
• W2586136145 cites W1968199513 @default.
• W2586136145 cites W1968748205 @default.
• W2586136145 cites W1969407754 @default.
• W2586136145 cites W1969933696 @default.
• W2586136145 cites W1971904761 @default.
• W2586136145 cites W1973073662 @default.
• W2586136145 cites W1973355859 @default.
• W2586136145 cites W1973951869 @default.
• W2586136145 cites W1974443997 @default.
• W2586136145 cites W1979489398 @default.
• W2586136145 cites W1980737446 @default.
• W2586136145 cites W1983292760 @default.
• W2586136145 cites W1986652317 @default.
• W2586136145 cites W1989962971 @default.
• W2586136145 cites W1999890305 @default.
• W2586136145 cites W2003786786 @default.
• W2586136145 cites W2006479362 @default.
• W2586136145 cites W2009245357 @default.
• W2586136145 cites W2012554369 @default.
• W2586136145 cites W2012793970 @default.
• W2586136145 cites W2019937274 @default.
• W2586136145 cites W2024044400 @default.
• W2586136145 cites W2027490649 @default.
• W2586136145 cites W2030721798 @default.
• W2586136145 cites W2031396743 @default.
• W2586136145 cites W2035602429 @default.
• W2586136145 cites W2048986076 @default.
• W2586136145 cites W2064444340 @default.
• W2586136145 cites W2064458799 @default.
• W2586136145 cites W2065174610 @default.
• W2586136145 cites W2066465889 @default.
• W2586136145 cites W2072607549 @default.
• W2586136145 cites W2072851819 @default.
• W2586136145 cites W2074262858 @default.
• W2586136145 cites W2075299720 @default.
• W2586136145 cites W2076066752 @default.
• W2586136145 cites W2076850627 @default.
• W2586136145 cites W2078596731 @default.
• W2586136145 cites W2079729488 @default.
• W2586136145 cites W2085981708 @default.
• W2586136145 cites W2089652494 @default.
• W2586136145 cites W2096040269 @default.
• W2586136145 cites W2097331875 @default.
• W2586136145 cites W2098661491 @default.
• W2586136145 cites W2100322627 @default.
• W2586136145 cites W2100658680 @default.
• W2586136145 cites W2100909095 @default.
• W2586136145 cites W2104450299 @default.
• W2586136145 cites W2106320907 @default.
• W2586136145 cites W2108730795 @default.
• W2586136145 cites W2109010866 @default.
• W2586136145 cites W2109193721 @default.
• W2586136145 cites W2110588878 @default.
• W2586136145 cites W2121582387 @default.
• W2586136145 cites W2122176812 @default.
• W2586136145 cites W2122874706 @default.
• W2586136145 cites W2126478587 @default.
• W2586136145 cites W2127004625 @default.
• W2586136145 cites W2135179733 @default.
• W2586136145 cites W2144463665 @default.
• W2586136145 cites W2145218167 @default.
• W2586136145 cites W2148430975 @default.
• W2586136145 cites W2149476429 @default.
• W2586136145 cites W2150849267 @default.
• W2586136145 cites W2154594399 @default.
• W2586136145 cites W2156281639 @default.
• W2586136145 cites W2161065172 @default.
• W2586136145 cites W2162595073 @default.
• W2586136145 cites W2164878099 @default.
• W2586136145 cites W2169003781 @default.
• W2586136145 cites W2170046832 @default.
• W2586136145 cites W2171536812 @default.
• W2586136145 cites W2172832204 @default.
• W2586136145 cites W2172946840 @default.
• W2586136145 cites W2207475551 @default.
• W2586136145 cites W2287668116 @default.
• W2586136145 cites W2302508466 @default.
• W2586136145 cites W2313852310 @default.
• W2586136145 cites W2317509225 @default.
• W2586136145 cites W2317542729 @default.
• W2586136145 cites W2321359620 @default.
• W2586136145 cites W2324430409 @default.
• W2586136145 cites W2326140448 @default.
• W2586136145 cites W2328959906 @default.
• W2586136145 cites W2330314364 @default.
• W2586136145 cites W2330597072 @default.
• W2586136145 cites W2331003041 @default.
• W2586136145 cites W2334766988 @default.

• next