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- W2586165718 abstract "There is consistent evidence from epidemiological studies that the cleaning professionals have a high risk of developing asthma. These workers are exposed to occupational agents of low and high molecular weight. It is important to produce evidence that this risk is related to work and not social conditions or other competitive factors, know the underlying pathological abnormality, and investigate possible agents. Thus, this study aims to assess if the work environment induces lung inflammation in asymptomatic workers, before the change of functional tests and the effectiveness of induced sputum and exhaled NO as early lung inflammation markers between professional cleaning workers. Workers were evaluated by comparing the sputum cytology, FeNO values, spirometry and PEF, during the work period and after the holidays. In our study, we found a significant increase in FEV1 values after the vacational period, despite of being within the normal range in both periods. The average peak flow measurements also was higher during the vacational period compared to the period of work, although not statistically significant. We found a reduction of the exhaled measured values of NO after the holidays, reduction of eosinophils, lymphocytes and macrophages in induced sputum cytology, performed after the holiday period. We demonstrate that the occupational environment to which professional cleaning non-domestic workers are exposed causes inflammation in the airways of asymptomatic workers. This inflammation can be measured by non-invasive methods such as induced sputum and FeNo, before the onset of changes in functional tests." @default.
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- W2586165718 date "2017-02-01" @default.
- W2586165718 modified "2023-09-27" @default.
- W2586165718 title "Inflammatory cell response, functional and biochemical features of the airways of professional cleaning workers upon exposure in the workplace" @default.
- W2586165718 doi "https://doi.org/10.1016/j.jaci.2016.12.034" @default.
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