Matches in SemOpenAlex for { <https://semopenalex.org/work/W2586833376> ?p ?o ?g. }
- W2586833376 endingPage "1396" @default.
- W2586833376 startingPage "1383" @default.
- W2586833376 abstract "A new atom transfer radical polymerization (ATRP) initiator, namely, 2-(1-(2-azidoethoxy)ethoxy)ethyl 2-bromo-2-methylpropanoate containing both “cleavable” acetal linkage and “clickable” azido group was synthesized. Well-defined azido-terminated poly(N-isopropylacrylamide)s (PNIPAAm-N3)s with molecular weights and dispersity in the range 11,000–19,000 g mol−1 and 1.20–1.28, respectively, were synthesized employing the initiator by ATRP. Acetal containing PCL-b-PNIPAAm block copolymer was obtained by alkyne–azide click reaction of azido-terminated PNIPAAm-N3 with propargyl-terminated PCL. Critical aggregation concentration (CAC) of PCL-b-PNIPAAm copolymer in aqueous solution was found to be 8.99 × 10−6 M. Lower critical solution temperature (LCST) of PCL-b-PNIPAAm copolymer was found to be 32 °C which was lower than that of the precursor PNIPAAm-N3 (36.4 °C). The effect of dual stimuli viz. temperature and pH on size and morphology of the assemblies of PCL-b-PNIPAAm block copolymer revealed that the copolymer below LCST assembled in spherical micelles which subsequently transformed to unstable vesicles above the LCST. Heating these assemblies above 40 °C led to the precipitation of PCL-b-PNIPAAm block copolymer. Whereas, at decreased pH, micelles of PCL-b-PNIPAAm copolymer disintegrate due to the cleavage of acetal linkage and precipitation of hydrophobic hydroxyl-terminated PCL. The encapsulated pyrene release kinetics from the micelles of synthesized PCL-b-PNIPAAm copolymer was found to be faster at higher temperature and at lower pH. © 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2017, 55, 1383–1396" @default.
- W2586833376 created "2017-02-17" @default.
- W2586833376 creator A5003503967 @default.
- W2586833376 creator A5077262928 @default.
- W2586833376 date "2017-02-09" @default.
- W2586833376 modified "2023-10-11" @default.
- W2586833376 title "Temperature and pH dual stimuli responsive PCL-<i>b</i>-PNIPAAm block copolymer assemblies and the cargo release studies" @default.
- W2586833376 cites W1558889624 @default.
- W2586833376 cites W1788569932 @default.
- W2586833376 cites W1905833881 @default.
- W2586833376 cites W1964963209 @default.
- W2586833376 cites W1967985930 @default.
- W2586833376 cites W1971038741 @default.
- W2586833376 cites W1974273490 @default.
- W2586833376 cites W1976769620 @default.
- W2586833376 cites W1982678425 @default.
- W2586833376 cites W1982814726 @default.
- W2586833376 cites W1983729374 @default.
- W2586833376 cites W1983950158 @default.
- W2586833376 cites W1992741184 @default.
- W2586833376 cites W1992981857 @default.
- W2586833376 cites W1993964194 @default.
- W2586833376 cites W1995180562 @default.
- W2586833376 cites W2004955040 @default.
- W2586833376 cites W2006897699 @default.
- W2586833376 cites W2015491525 @default.
- W2586833376 cites W2020640270 @default.
- W2586833376 cites W2026855042 @default.
- W2586833376 cites W2031721610 @default.
- W2586833376 cites W2049829880 @default.
- W2586833376 cites W2050588701 @default.
- W2586833376 cites W2051577093 @default.
- W2586833376 cites W2053698400 @default.
- W2586833376 cites W2054201768 @default.
- W2586833376 cites W2054968161 @default.
- W2586833376 cites W2062084562 @default.
- W2586833376 cites W2062923291 @default.
- W2586833376 cites W2070143261 @default.
- W2586833376 cites W2072748023 @default.
- W2586833376 cites W2080116201 @default.
- W2586833376 cites W2082442897 @default.
- W2586833376 cites W2089853276 @default.
- W2586833376 cites W2092321937 @default.
- W2586833376 cites W2135155005 @default.
- W2586833376 cites W2138853132 @default.
- W2586833376 cites W2139451054 @default.
- W2586833376 cites W2150085932 @default.
- W2586833376 cites W2157891696 @default.
- W2586833376 cites W2257328744 @default.
- W2586833376 cites W2312995599 @default.
- W2586833376 cites W2318239347 @default.
- W2586833376 cites W2321241157 @default.
- W2586833376 cites W2328308165 @default.
- W2586833376 cites W2330014148 @default.
- W2586833376 cites W2332407828 @default.
- W2586833376 cites W2342138791 @default.
- W2586833376 cites W2343196885 @default.
- W2586833376 cites W2344361295 @default.
- W2586833376 cites W2411048407 @default.
- W2586833376 cites W2469676770 @default.
- W2586833376 cites W2524362582 @default.
- W2586833376 cites W2532645043 @default.
- W2586833376 cites W2546351144 @default.
- W2586833376 doi "https://doi.org/10.1002/pola.28508" @default.
- W2586833376 hasPublicationYear "2017" @default.
- W2586833376 type Work @default.
- W2586833376 sameAs 2586833376 @default.
- W2586833376 citedByCount "16" @default.
- W2586833376 countsByYear W25868333762017 @default.
- W2586833376 countsByYear W25868333762018 @default.
- W2586833376 countsByYear W25868333762019 @default.
- W2586833376 countsByYear W25868333762020 @default.
- W2586833376 countsByYear W25868333762022 @default.
- W2586833376 countsByYear W25868333762023 @default.
- W2586833376 crossrefType "journal-article" @default.
- W2586833376 hasAuthorship W2586833376A5003503967 @default.
- W2586833376 hasAuthorship W2586833376A5077262928 @default.
- W2586833376 hasConcept C111998727 @default.
- W2586833376 hasConcept C11268172 @default.
- W2586833376 hasConcept C121120078 @default.
- W2586833376 hasConcept C150539798 @default.
- W2586833376 hasConcept C15920480 @default.
- W2586833376 hasConcept C178790620 @default.
- W2586833376 hasConcept C184651966 @default.
- W2586833376 hasConcept C185592680 @default.
- W2586833376 hasConcept C188027245 @default.
- W2586833376 hasConcept C188109995 @default.
- W2586833376 hasConcept C44228677 @default.
- W2586833376 hasConcept C521977710 @default.
- W2586833376 hasConcept C69610077 @default.
- W2586833376 hasConceptScore W2586833376C111998727 @default.
- W2586833376 hasConceptScore W2586833376C11268172 @default.
- W2586833376 hasConceptScore W2586833376C121120078 @default.
- W2586833376 hasConceptScore W2586833376C150539798 @default.
- W2586833376 hasConceptScore W2586833376C15920480 @default.
- W2586833376 hasConceptScore W2586833376C178790620 @default.
- W2586833376 hasConceptScore W2586833376C184651966 @default.
- W2586833376 hasConceptScore W2586833376C185592680 @default.