Matches in SemOpenAlex for { <https://semopenalex.org/work/W2587093982> ?p ?o ?g. }
- W2587093982 abstract "This chapter focuses on the enzymatic mono-ADP-ribosylation of the G protein subunits, catalyzed by both bacterial toxins and eukaryotic enzymes, and discusses the mechanisms and potential role of this reaction in mammals. Heterotrimeric G proteins play a crucial role in determining the specificity of the cellular response to extracellular signals. Among the mechanisms controlling G-protein functions are a variety of covalent modifications, relevant in both normal and pathological conditions. The known post-translational modifications occurring on G protein α and βγ subunits include lipid modifications, which are required for targeting to the plasma membrane of α and βγ and for the interaction of α with either βγ or effectors or RGS proteins; phosphorylation, which affects the interactions between α and βγ, and between G proteins with either receptors or effectors; and finally mono-ADP-ribosylation, whose function has not yet been fully defined." @default.
- W2587093982 created "2017-02-17" @default.
- W2587093982 creator A5027586402 @default.
- W2587093982 creator A5047098934 @default.
- W2587093982 date "2003-01-01" @default.
- W2587093982 modified "2023-09-27" @default.
- W2587093982 title "Mono-ADP-Ribosylation of Heterotrimeric G Proteins" @default.
- W2587093982 cites W147389763 @default.
- W2587093982 cites W1492784537 @default.
- W2587093982 cites W1513028020 @default.
- W2587093982 cites W1533877914 @default.
- W2587093982 cites W1557026675 @default.
- W2587093982 cites W1557173787 @default.
- W2587093982 cites W1580552987 @default.
- W2587093982 cites W1592736409 @default.
- W2587093982 cites W1606317888 @default.
- W2587093982 cites W1633576971 @default.
- W2587093982 cites W1639032582 @default.
- W2587093982 cites W1793900875 @default.
- W2587093982 cites W1837789756 @default.
- W2587093982 cites W1933358967 @default.
- W2587093982 cites W1935811184 @default.
- W2587093982 cites W1964257857 @default.
- W2587093982 cites W1965381503 @default.
- W2587093982 cites W1971524591 @default.
- W2587093982 cites W1973820404 @default.
- W2587093982 cites W1974971121 @default.
- W2587093982 cites W1975998142 @default.
- W2587093982 cites W1986960469 @default.
- W2587093982 cites W1988204900 @default.
- W2587093982 cites W1991320177 @default.
- W2587093982 cites W2005580422 @default.
- W2587093982 cites W2014379339 @default.
- W2587093982 cites W2018317584 @default.
- W2587093982 cites W2025671442 @default.
- W2587093982 cites W2028813908 @default.
- W2587093982 cites W2032668742 @default.
- W2587093982 cites W2040080953 @default.
- W2587093982 cites W2041959419 @default.
- W2587093982 cites W2045509195 @default.
- W2587093982 cites W2049495066 @default.
- W2587093982 cites W2056239892 @default.
- W2587093982 cites W2058902988 @default.
- W2587093982 cites W2062989107 @default.
- W2587093982 cites W2065977276 @default.
- W2587093982 cites W2069974281 @default.
- W2587093982 cites W2070569312 @default.
- W2587093982 cites W2075651726 @default.
- W2587093982 cites W2081485424 @default.
- W2587093982 cites W2094549029 @default.
- W2587093982 cites W2103974485 @default.
- W2587093982 cites W2105050513 @default.
- W2587093982 cites W2111056759 @default.
- W2587093982 cites W2112072577 @default.
- W2587093982 cites W2115491456 @default.
- W2587093982 cites W2120054149 @default.
- W2587093982 cites W2138529060 @default.
- W2587093982 cites W2146675221 @default.
- W2587093982 cites W2150390278 @default.
- W2587093982 cites W2168839532 @default.
- W2587093982 cites W2342300047 @default.
- W2587093982 cites W309933625 @default.
- W2587093982 cites W4233722678 @default.
- W2587093982 cites W4252215306 @default.
- W2587093982 cites W55558057 @default.
- W2587093982 doi "https://doi.org/10.1016/b978-012124546-7/50583-0" @default.
- W2587093982 hasPublicationYear "2003" @default.
- W2587093982 type Work @default.
- W2587093982 sameAs 2587093982 @default.
- W2587093982 citedByCount "2" @default.
- W2587093982 crossrefType "book-chapter" @default.
- W2587093982 hasAuthorship W2587093982A5027586402 @default.
- W2587093982 hasAuthorship W2587093982A5047098934 @default.
- W2587093982 hasConcept C11960822 @default.
- W2587093982 hasConcept C139407321 @default.
- W2587093982 hasConcept C170493617 @default.
- W2587093982 hasConcept C181199279 @default.
- W2587093982 hasConcept C185592680 @default.
- W2587093982 hasConcept C45510557 @default.
- W2587093982 hasConcept C51785407 @default.
- W2587093982 hasConcept C55493867 @default.
- W2587093982 hasConcept C75520062 @default.
- W2587093982 hasConcept C80631254 @default.
- W2587093982 hasConcept C86803240 @default.
- W2587093982 hasConcept C95444343 @default.
- W2587093982 hasConceptScore W2587093982C11960822 @default.
- W2587093982 hasConceptScore W2587093982C139407321 @default.
- W2587093982 hasConceptScore W2587093982C170493617 @default.
- W2587093982 hasConceptScore W2587093982C181199279 @default.
- W2587093982 hasConceptScore W2587093982C185592680 @default.
- W2587093982 hasConceptScore W2587093982C45510557 @default.
- W2587093982 hasConceptScore W2587093982C51785407 @default.
- W2587093982 hasConceptScore W2587093982C55493867 @default.
- W2587093982 hasConceptScore W2587093982C75520062 @default.
- W2587093982 hasConceptScore W2587093982C80631254 @default.
- W2587093982 hasConceptScore W2587093982C86803240 @default.
- W2587093982 hasConceptScore W2587093982C95444343 @default.
- W2587093982 hasLocation W25870939821 @default.
- W2587093982 hasOpenAccess W2587093982 @default.
- W2587093982 hasPrimaryLocation W25870939821 @default.