Matches in SemOpenAlex for { <https://semopenalex.org/work/W2587226921> ?p ?o ?g. }
- W2587226921 endingPage "269" @default.
- W2587226921 startingPage "264" @default.
- W2587226921 abstract "Despite many advances in surgery and technology, colonic anastomosis remains a challenge after colonic resection. The purpose of this study is to compare the safety of using diclofenac sodium and paracetamol for analgesia in colonic anastomosis on rats. Wistar–Hannover rats were randomly allocated to four groups: Group 1, sham-operated group; Group 2, control group; Group 3, diclofenac sodium group; Group 4, paracetamol group. After laparotomy, the left colon was transected and a single-layer anastomosis was made with 5/0 vicryl in Groups 2, 3, and 4. Only laparotomy was performed in Group 1. After anastomosis, we administered saline to Group 2, diclofenac sodium to Group 3, and paracetamol to Group 4 for 7 days. Then, all animals were decapitated. The anastomotic region was resected, and bursting pressure was measured. Then, the specimen was sent to the laboratory for histological examination and hydroxyproline analysis. Bursting pressure and hydroxyproline level were significantly higher in the paracetamol group (p < 0.05). When we looked at the fibrosis levels of these groups, it was also higher in paracetamol group. Bursting pressure, hydroxyproline levels, and fibrosis levels indicate that the perioperative use of paracetamol for analgesia when undergoing colonic anastomosis is safer than diclofenac sodium." @default.
- W2587226921 created "2017-02-17" @default.
- W2587226921 creator A5007059217 @default.
- W2587226921 creator A5018666359 @default.
- W2587226921 creator A5018927311 @default.
- W2587226921 creator A5020931267 @default.
- W2587226921 creator A5033568766 @default.
- W2587226921 creator A5040226108 @default.
- W2587226921 creator A5052805451 @default.
- W2587226921 creator A5054130433 @default.
- W2587226921 creator A5066604533 @default.
- W2587226921 creator A5070494907 @default.
- W2587226921 creator A5070698426 @default.
- W2587226921 creator A5089584603 @default.
- W2587226921 date "2018-05-01" @default.
- W2587226921 modified "2023-10-14" @default.
- W2587226921 title "Role of diclofenac sodium and paracetamol on colonic anastomosis: An experimental rodent model" @default.
- W2587226921 cites W1924475506 @default.
- W2587226921 cites W1946784230 @default.
- W2587226921 cites W1965631590 @default.
- W2587226921 cites W1971280137 @default.
- W2587226921 cites W1980632854 @default.
- W2587226921 cites W1982914159 @default.
- W2587226921 cites W1983198572 @default.
- W2587226921 cites W1987007764 @default.
- W2587226921 cites W2010075585 @default.
- W2587226921 cites W2012720534 @default.
- W2587226921 cites W2015776777 @default.
- W2587226921 cites W2023405662 @default.
- W2587226921 cites W2027510476 @default.
- W2587226921 cites W2027685770 @default.
- W2587226921 cites W2031960481 @default.
- W2587226921 cites W2051363290 @default.
- W2587226921 cites W2053304919 @default.
- W2587226921 cites W2062505263 @default.
- W2587226921 cites W2062692788 @default.
- W2587226921 cites W2074989647 @default.
- W2587226921 cites W2089203371 @default.
- W2587226921 cites W2089984325 @default.
- W2587226921 cites W2093367934 @default.
- W2587226921 cites W2099419613 @default.
- W2587226921 cites W2106362577 @default.
- W2587226921 cites W2109435454 @default.
- W2587226921 cites W2109802716 @default.
- W2587226921 cites W2110119261 @default.
- W2587226921 cites W2112830331 @default.
- W2587226921 cites W2130289134 @default.
- W2587226921 cites W2150205603 @default.
- W2587226921 cites W2156590441 @default.
- W2587226921 cites W2168240567 @default.
- W2587226921 cites W2344809002 @default.
- W2587226921 doi "https://doi.org/10.1016/j.asjsur.2017.01.002" @default.
- W2587226921 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28190750" @default.
- W2587226921 hasPublicationYear "2018" @default.
- W2587226921 type Work @default.
- W2587226921 sameAs 2587226921 @default.
- W2587226921 citedByCount "10" @default.
- W2587226921 countsByYear W25872269212019 @default.
- W2587226921 countsByYear W25872269212020 @default.
- W2587226921 countsByYear W25872269212021 @default.
- W2587226921 countsByYear W25872269212022 @default.
- W2587226921 countsByYear W25872269212023 @default.
- W2587226921 crossrefType "journal-article" @default.
- W2587226921 hasAuthorship W2587226921A5007059217 @default.
- W2587226921 hasAuthorship W2587226921A5018666359 @default.
- W2587226921 hasAuthorship W2587226921A5018927311 @default.
- W2587226921 hasAuthorship W2587226921A5020931267 @default.
- W2587226921 hasAuthorship W2587226921A5033568766 @default.
- W2587226921 hasAuthorship W2587226921A5040226108 @default.
- W2587226921 hasAuthorship W2587226921A5052805451 @default.
- W2587226921 hasAuthorship W2587226921A5054130433 @default.
- W2587226921 hasAuthorship W2587226921A5066604533 @default.
- W2587226921 hasAuthorship W2587226921A5070494907 @default.
- W2587226921 hasAuthorship W2587226921A5070698426 @default.
- W2587226921 hasAuthorship W2587226921A5089584603 @default.
- W2587226921 hasBestOaLocation W25872269211 @default.
- W2587226921 hasConcept C126322002 @default.
- W2587226921 hasConcept C141071460 @default.
- W2587226921 hasConcept C2776881634 @default.
- W2587226921 hasConcept C2777327002 @default.
- W2587226921 hasConcept C2777397205 @default.
- W2587226921 hasConcept C2779797417 @default.
- W2587226921 hasConcept C2779826273 @default.
- W2587226921 hasConcept C2780778865 @default.
- W2587226921 hasConcept C2908765736 @default.
- W2587226921 hasConcept C42219234 @default.
- W2587226921 hasConcept C71924100 @default.
- W2587226921 hasConcept C8443397 @default.
- W2587226921 hasConcept C98274493 @default.
- W2587226921 hasConceptScore W2587226921C126322002 @default.
- W2587226921 hasConceptScore W2587226921C141071460 @default.
- W2587226921 hasConceptScore W2587226921C2776881634 @default.
- W2587226921 hasConceptScore W2587226921C2777327002 @default.
- W2587226921 hasConceptScore W2587226921C2777397205 @default.
- W2587226921 hasConceptScore W2587226921C2779797417 @default.
- W2587226921 hasConceptScore W2587226921C2779826273 @default.
- W2587226921 hasConceptScore W2587226921C2780778865 @default.
- W2587226921 hasConceptScore W2587226921C2908765736 @default.