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- W2587299572 abstract "Objectives: A study was conducted to examine the in vitro cytotoxic effects of Echitamine chloride (EC), a plant alkaloid extracted from the bark of Alstonia scholaris. Since vitamin A was found to enhance the anticancer effects of several anticancer drugs, the synergistic effects of these two drugs were also studied.Methods: Echitamine chloride at a concentration of 200'M and Vitamin A at a concentration of 10 'M were added alone as well as in combination to the Ehrlich Ascites Carcinoma (EAC) cell cultures. Cell viability, antioxidant enzyme status, lipid peroxidation and 3H -Thymidine incorporation were studied. Results: The cultures treated with EC and vitamin A combination showed significant cytotoxic effect than the cultures treated with individual drugs. Conclusion: It may be concluded that EC in combination with vitamin A has an enhanced cytotoxic effect on Ehrlich Ascites Carcinoma cell culture." @default.
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- W2587299572 date "1997-01-01" @default.
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- W2587299572 title "Enhancement of the cytotoxic effects of Echitamine chloride by vitamin A: An in vitro study on Ehrlich ascites carcinoma cell culture" @default.
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